- Bryan Trevor Sewell (University of Cape Town)
Dr Robert Skelton (University of California Berkeley)
MicroCT has tremendous potential to provide novel insights into plant form and function My research uses this and other, novel, non-invasive optical techniques to view the process of leaf and stem xylem embolism formation within intact plants to resolve long-standing questions in plant physiology. Here, I will highlight two recent experiments performed at the Australian Synchrotron in...
25. Heterologous expression, crystallization and structural determination of Schistosoma mansoni Universal stress G4LZI3 protein by X-ray crystallography.
Prof. Abidemi Paul Kappo (University of Zululand)
The formation of high quality and perfect crystals forms the bottleneck and rate-limiting step for structure determination by X-ray crystallography. Protein crystallography has formed an intricate part of the chemical, biotechnology and pharmaceutical industry as an important tool towards drug design, protein engineering and in understanding various biological systems. In this study, a...
Dr Thandeka Moyo (National Institute for Communicable Diseases)
Thandeka Moyo1,2, Cathrine Scheepers1, Prudence Kgagudi1, Rutendo Ziki1, Lynn Morris1, 2, 3, Penny L. Moore1, 2, 3 1National Institute for Communicable Diseases, Johannesburg, South Africa 2University of the Witwatersrand, Johannesburg, South Africa 3Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa HIV broadly neutralizing antibody (bNAb)...
3. Biophysical characterization of Plasmodium falciparum Hsp70-Hsp90 organizing protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers
Dr Stanley Makumre (University of Venda)
Plasmodium falciparum causes the most lethal form of malaria. The cooperation of heat shock protein (Hsp) 70 and 90 is important for the folding of a select number of cellular proteins that are crucial for cyto-protection and development of the parasites. Hsp70 and Hsp90 are brought into a functional complex that allows substrate exchange by stress-inducible protein 1 (STI1), also known as...