2-6 September 2013
STIAS Conference Centre
Africa/Johannesburg timezone

Biomedical applications of optics

4 Sep 2013, 14:00
STIAS Conference Centre

STIAS Conference Centre

Stellenbosch Institute for Advanced Study Wallenberg Research Centre 10 Marais Road Stellenbosch South Africa www.stias.ac.za
Poster Presentation


Dr Patience Mthunzi (CSIR - NLC)

Abstract content <br>(Max 300 words)<br><a href="http://indico.saip.org.za/getFile.py/access?resId=0&materialId=2&confId=28" target="_blank">Special Chars</a>

Mammalian cells can be optically micro-manipulated in-vitro to promote embryonic stem cell research, neurodegenerative disorder studies, human immunodeficiency virus (HIV-1) investigations and cancer research science. In this work, lasers of different regimes are employed as they possess special properties that allow classical biomedical applications. Studies toward the interaction of laser light, nanomaterials and biological materials can lead to an understanding of a wealth of disease conditions and result in photonics-based therapies and diagnostic tools. In this talk; firstly, optical transfection and differentiation of embryonic stem cells is presented. Secondly, somatic and dendritic phototransfection of neuroblastoma cells on graphene substrates is shown. Thirdly, using different beam shapes photo-translocation of HIV-1 drugs into TZM-bl cells is given. Finally, optical trapping and sorting of cancerous from healthy ones is demonstrated.

Primary author

Dr Patience Mthunzi (CSIR - NLC)


Prof. Andrew Forbes (National Laser Center, CSIR) Dr Jamie Warner (Department of Materials, University of Oxford) Mr Kuang He (Department of Materials, University of Oxford) Prof. Maria Papathanasopoulos (Department of Molecular Medicine and Haematology, University of the Witwatersrand Medical School) Mr Sandile Ngcobo (National Laser Center, CSIR) Ms Thulile Khanyile (National Laser Center, CSIR)

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