5-7 May 2015
Mabula Game Lodge
Africa/Johannesburg timezone
Conference paper submission deadline is 8 May

Synthesis and Characterization of luminescence magnetic nanocomposite for biomedicine application

7 May 2015, 14:30
20m
Mabula Game Lodge

Mabula Game Lodge

Oral Presentations SACPM Presentations

Speaker

Mr Kiplagat Ayabei (University of the western cape)

Description

1. Introduction In the recent past, magnetic materials and semiconductor inorganic materials have been developed and applied (as independent) in fields including biomedicine, especially biotechnological processes imaging, tracking, and separating biological molecules or cells. Processes of biomedical diagnosis and therapy require nanometer scale particles featuring characteristics such as magnetization and fluorescence [1-4]. In the last two decades research has been focused on fabrication of QDs constituting elements of groups II-IV owing to their potential application in lasers, light emitting diodes and biological studies. However, biological applications of the as-prepared QDs were limited by presence of highly toxic Cadmium core. Strategies have been employed to alleviate toxicity of Cd based core coating it with less toxic materials such as a ZnS shell. However, exposure to UV light or oxidation results in the release of cadmium via surface oxidation. In the current study new type of Indium based quantum dot was synthesized and conjugated to the magnetic nanoparticles. The QD were characterized by PL, HRTEM, XRD, SQUID and FTIR. 2. Results and Discussion The photoluminescence characteristics of the coupled and uncoupled indium based quantum dots were investigated to determine whether the fluorescing property could be retained in the bifunctional system. Generally, the PL intensity of the QDs was observed to remain almost the same with slight blue shift, most probably due to quenching effects of magnetic nanoparticles (MNPs). Equally the quenching effect of the QDs on the magnetic nanomaterials was also investigated. The toxicity of the as prepared nanoparticles was investigated and results will be reported during the conference.

Please provide the name and email address of your supervisor.

Prof Martin O. onani
Email address:monani@uwc.ac.za

At what level of studies are you currently? (Hons/MSc/PhD)

pHD

Are you currently a postgraduate student? (Yes/No)

Yes

Primary author

Mr Kiplagat Ayabei (University of the western cape)

Co-authors

Prof. Francis Dejene (University of free state) Prof. Martin Onani (University of the Western Cape) Prof. Mervin Meyer (University of the western cape) Prof. Teresa Akenga (University of Eldoret)

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