Conveners
Structural Biology: Structural Biology
- Tjaart Krüger (University of Pretoria)
Prof.
Bryan Trevor Sewell
(University of Cape Town)
, Dr
Dewald van Heerden
(University of Cape Town)
28/09/2023, 09:00
Structural Biology
Oral Presentation
Our goal is to determine the mechanisms of the nitrilase superfamily enzymes. These enzymes have common features such as their fold and conserved residues in their active sites (two glutamates, a lysine and a cysteine) but have a range of different activities. The superfamily derives its name from the nitrilases that convert nitriles to the corresponding carboxylic acids and ammonia, but most...
