1-8 July 2022
Virtual Conference
Africa/Johannesburg timezone
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Photobioinhibitory Effect of Laser on Resistant MCF-7 Cancer Cell Line

Not scheduled
50m
Zoom Platform (Virtual Conference)

Zoom Platform

Virtual Conference

Poster Presentation Track C - Photonics Poster Session

Speaker

Ms Nosipho Fakudze (University of Johannesburg)

Description

Cancer affects individuals globally and breast cancer is the leading cancer in women in South Africa. The most common new cases of cancer include breast cancer, prostate, lung, and colorectal cancers. Photobiomodulation is a non-invasive
treatment that can be used in the treatment of tendinopathies, osteoarthritis, nerve injuries, wound healing, and some malignancies. Photobiomodulation has mixed finding when it comes to cancer treatment with results of no effect and some with positive effects. This study aimed to investigate the inhibitory effect of a 680 nm laser on Doxorubicin (DOX) resistant MCF-7 cancer cells. These cells were treated with 5
μM Dox alone and the same concentration of Dox combined with 20 J/cm2 laser irradiation. The findings of this pilot study suggests that cells treated with Dox and laser has a significant cytotoxic effect of decreased cell proliferation and morphological damage compared to the untreated control cells and laser treated cells alone. These findings invites further investigation to explore any possible combination of laser
irradiation in the treatment of cancer that are resistant to chemotherapy.

Level for award;(Hons, MSc, PhD, N/A)?

MSc

Apply to be considered for a student ; award (Yes / No)? Yes

Primary author

Ms Nosipho Fakudze (University of Johannesburg)

Co-author

Prof. Blassan George (University of Johannesburg)

Presentation Materials

There are no materials yet.