22-26 March 2021
Zoom Conference
Africa/Johannesburg timezone
Biophysics in and for Africa

Promising antiviral, antimicrobial and therapeutic properties of green nanoceria

23 Mar 2021, 16:00
20m
Zoom Conference

Zoom Conference

Virtual Event
Oral Presentation Biophysics and maternal health Biophysics and maternal health

Speaker

Hamza Mohamed (iThemba LABS/UNISA)

Description

Aim: To demonstrate synthesis of cerium oxide nanoparticles (CeO2 NPs) by a green method using Hyphaene thebaica, and investigate their therapeutic applications. Materials & methods: Structural, vibrational and luminescent properties were established using x-ray diffraction, Fourier transformed infrared spectroscopy, Raman spectroscopy, ultraviolet absorption spectroscopy, selected area electron diffraction, electron microscopy and photolumincence spectroscopy. Therapeutic properties were established using different in vitro assays. Results: CeO2 NPs were determined to be crystalline in nature with a grain size of approximately 14 nm. They had characteristic Ce–O vibration at 481 cm-1. Photoluminescence spectra revealed broad bands at 463 and 600 nm. ζ potential was recorded as -17.2 mV. Potent antimicrobial and antiviral properties with hemocompatibility were reported. Conclusion: Biosynthesized CeO2 NPs revealed multifunctional therapeutic properties.

Primary author

Hamza Mohamed (iThemba LABS/UNISA)

Presentation Materials

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