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SUMMARY:Investigation of Biomimetic Coatings on Glassy Carbon and Ti-6Al-4
 V Substrates: Impact of Varying Surface Preparation Methods
DTSTART;VALUE=DATE-TIME:20241118T100000Z
DTEND;VALUE=DATE-TIME:20241118T101500Z
DTSTAMP;VALUE=DATE-TIME:20261010T201117Z
UID:indico-contribution-9893@events.saip.org.za
DESCRIPTION:Speakers: Unaisa Dockrat (University of Pretoria)\n**Investiga
 tion of Biomimetic Coatings on Glassy Carbon and Ti-6Al-4V Substrates: Imp
 act of Varying Surface Preparation Methods**\n\nUnaisa Dockrat1\, Johan.B.
  Malherbe 1\, Tshepo.P. Ntsoane2\, Thabsile.T. Thabethe1\n\n1Physics Depar
 tment\, University of Pretoria\, Hatfield\, South Africa. \n2Physics Depar
 tment\, South African Nuclear Energy Corporation\, Pretoria\, South Africa
 .\n\nCorresponding author: unaisa.dockrat@tuks.co.za\n\n 1. Introduction \
 nBiomimetic coatings\, an innovative advancement in biomedical engineering
 \, replicate the intricate mechanisms and superior properties observed in 
 biological systems to enhance the performance\, durability\, reliability\,
  and biocompatibility of biomedical implants [1-2]. These coatings aim to 
 improve implant integration with the human body\, addressing the challenge
 s of traditional coatings like thermally sprayed hydroxyapatite (HAp)\, wh
 ich can suffer from inherent residual stress\, undesirable thermal product
 s\, poor biocompatibility\, infection risk\, and inadequate tissue integra
 tion [2]. By imitating natural biochemical processes\, biomimetic coatings
  with better cellular adhesion\, proliferation\, and differentiation [3] c
 an be produced. This study explores biomimetic deposition on Ti-6Al-4V (Ti
 64) and glassy carbon (GC) substrates\, pretreated with sandblasting\, pla
 sma etching\, and polishing\, and then immersed in simulated bodily fluid 
 (SBF) for 56 days. The resulting coatings were analyzed using scanning ele
 ctron microscopy (SEM) for surface morphology\, energy-dispersive X-ray sp
 ectroscopy (EDS) for elemental analysis\, atomic force microscopy (AFM)\, 
 and X-ray diffraction (XRD) to evaluate their structural and compositional
  properties.\n\n 2. Results\n\nEDS analysis revealed higher Ca and P on co
 atings deposited on plasma-etched and polished GC substrates\, while sandb
 lasted Ti64 substrates showed higher O\, Ca\, and P. Plasma-etched GC and 
 sandblasted Ti64 apatite coatings resembled thermally sprayed HAp layers o
 n Ti64\, indicating similar elemental compositions. Ti64 substrates subjec
 ted to polishing and plasma etching had lower element percentages due to p
 re-treatment. SEM images showed distinct surface morphologies: GC substrat
 es had tightly packed spherical particles creating a rough texture\, while
  sandblasted Ti64 substrates exhibited densely packed spherical clusters a
 nd plasma-etched Ti64 samples had small\, uneven clusters forming a porous
  texture. XRD confirmed coatings on polished and plasma-etched GC and the 
 sandblasted and plasma-etched Ti64 as hydroxyapatite with fine grain size.
  XRD analysis confirmed all patterns to display distinct peaks correspondi
 ng to apatite\, confirming successful biomimetic apatite coating formation
 . The AFM measured the Young's modulus of the coatings and observed values
  within the range comparable to that of human cortical bone (17–25 GPa) 
 [4]. These findings highlight the success of biomimetic coatings\, which i
 ndeed produce the apatite coating needed for biomaterial implants. Synchro
 tron radiation studies will also be carried out to investigate the relatio
 nships between coating microstructure\, elemental composition\, and overal
 l coating stability. \n\n\n\nReferences\n\n[1] Smith\, A. M.\, & Callow\, 
 J. A. (2016). Biomimetic Coatings for Biomedical Applications: Advances in
  Synthesis and Applications. Journal of Biomedical Materials Research Part
  A\, 104(6)\, 1457-1472. doi:10.1002/jbm.a.35781.\n[2] Zhao\, L.\, Wang\, 
 H.\, Huo\, K.\, Cui\, L.\, Zhang\, W.\, Ni\, H.\, ... & Chu\, P. K. (2011)
 . Antibacterial nano-structured titanium for biomedical applications. Nano
 medicine: Nanotechnology\, Biology and Medicine\, 7(2)\, 177-185. doi:10.1
 016/j.nano.2010.10.004.\n[3] Wang\, X.\, Li\, Y.\, Wei\, J.\, & de Groot\,
  K. (2002). Development of biomimetic nano-hydroxyapatite/poly(hexamethyle
 ne adipamide) composites. Biomaterials\, 23(24)\, 4787-4791. doi:10.1016/S
 0142-9612(02)00207-0.\n[4] D. T. Reilly and A. H. Burstein\, "The elastic 
 and ultimate properties of compact bone tissue\," Journal of Biomechanics\
 , vol. 8\, no. 6\, pp. 393-405\, 1975.\n\nhttps://events.saip.org.za/event
 /249/contributions/9893/
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URL:https://events.saip.org.za/event/249/contributions/9893/
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