BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//CERN//INDICO//EN
BEGIN:VEVENT
SUMMARY:Structural Biology at the ESRF: present and future
DTSTART;VALUE=DATE-TIME:20191112T120000Z
DTEND;VALUE=DATE-TIME:20191112T123000Z
DTSTAMP;VALUE=DATE-TIME:20260911T102757Z
UID:indico-contribution-2155@events.saip.org.za
DESCRIPTION:Speakers: Gordon Leonard (ESRF)\nThe ESRF’s facilities for S
 tructural Biology comprise 6 end-stations for macromolecular crystallograp
 hy (MX) 1\, one end-station for BioSAXS experiments 2 and one end-station 
 based around a Titan Krios cryo-electron microscope 3. These are supplemen
 ted by a number of support laboratories including the iCOS facility for in
  crystallo optical spectroscopy 4 and a facility for the high pressure cry
 o-cooling and/or derivatisation of crystals of biological macromolecules 5
 . This talk will describe the instrumentation and experimental possibiliti
 es available on these end-stations\, with a particular emphasis on automat
 ion\, remote access and mail-in services.\nThe ESRF Extremely Brilliant So
 urce (EBS) project (see http://www.esrf.fr/about/upgrade for details) will
  provide benefits for many areas of synchrotron-based science. This presen
 tation will thus also look ahead to the evolution of the ESRF’s faciliti
 es for Structural Biology post-2020\, focusing on the possibilities for se
 rial crystallography and time-resolved MX\, which ESRF-EBS X-ray beams wil
 l facilitate.\n\n1.    Mueller-Dieckmann\, C. et al. The status of the mac
 romolecular crystallography beamlines at the European Synchrotron Radiatio
 n Facility. Eur. Phys. J. Plus 130: 70 (2015)\; doi /https//doi.org/10.114
 0/epjp/i2015-15070-0.\n2.    Pernot\, P.\, et al. Upgraded ESRF BM29 beaml
 ine for SAXS on macromolecules in solution.  J. Synchrotron Rad. 20\, 660-
 664 (2017).\n3.    Kandiah\, E. et al. CM01: a facility for cryo-electron 
 microscopy at the European Synchrotron. Acta Cryst. D75\, 528-535 (2019).\
 n4.    von Stetten\, D. et al.  In crystallo optical spectroscopy (icOS) a
 s a complementary tool on the macromolecular crystallography beamlines of 
 the ESRF.  Acta Cryst. D71\, 15-26 (2015).\n5.    Lafumat\, B.\, et al. Ga
 s-sensitive biological crystals processed in pressurized oxygen and krypto
 n atmospheres: deciphering gas channels in proteins using a novel `soak-an
 d-freeze' methodology. J. Appl. Cryst. 49\, 1478-1487 (2016).\n\nhttps://e
 vents.saip.org.za/event/173/contributions/2155/
LOCATION:
URL:https://events.saip.org.za/event/173/contributions/2155/
END:VEVENT
END:VCALENDAR