BEGIN:VCALENDAR VERSION:2.0 PRODID:-//CERN//INDICO//EN BEGIN:VEVENT SUMMARY:ALBA and the AfLS Roadmap DTSTART;VALUE=DATE-TIME:20190201T150000Z DTEND;VALUE=DATE-TIME:20190201T151000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1621@events.saip.org.za DESCRIPTION:Speakers: Caterina Biscari (ALBA Synchrotron)\nhttps://events. saip.org.za/event/145/contributions/1621/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1621/ END:VEVENT BEGIN:VEVENT SUMMARY:Advanced Materials Characterization Using Powder Diffraction Techn iques and the Powder Diffraction File DTSTART;VALUE=DATE-TIME:20190130T150000Z DTEND;VALUE=DATE-TIME:20190130T152000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1622@events.saip.org.za DESCRIPTION:Speakers: Tom Blanton (International Centre for Diffraction Da ta)\nAdvanced Materials Characterization Using Powder Diffraction Techniqu es and the Powder Diffraction File\n\nhttps://events.saip.org.za/event/145 /contributions/1622/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1622/ END:VEVENT BEGIN:VEVENT SUMMARY:Sharing structures around the world DTSTART;VALUE=DATE-TIME:20190130T140000Z DTEND;VALUE=DATE-TIME:20190130T143000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1577@events.saip.org.za DESCRIPTION:Speakers: Suzanna Ward (The Cambridge Crystallographic Data Ce ntre\, Cambridge\, UK)\nCrystallography is extremely powerful in research and education for two key reasons. Firstly\, it\nis often described as the ‘gold standard’ characterization technique because it can provide\nde finitive proof of the structure of chemical compounds. Secondly\, the crys tallographic\ncommunity itself is remarkable in terms of exemplary data sh aring practices which have allowed\nscientists worldwide to gain new insig hts and knowledge from the collaborative collection of\ndata.\nThis presen tation will look at how crystallographic data is curated and shared throug h a variety\nof databases including the Cambridge Structural Database (CSD )\, a collection of nearly one\nmillion organic and metal-organic crystal structures. We will detail the methods that we use to\nfacilitate data dep osition\, storage and accessibility\, and describe the workflows that we h ave in\nplace to manage data at the Cambridge Crystallographic Data Centre (CCDC). We will then go\non to highlight how you can use the CSD and CCDC services to improve and validate your own\nstructural data and explore ho w structural data can be used in education.\nFinally\, we will celebrate c rystallography from the Pan African Community by highlighting their\ncontr ibutions to the CSD before reflecting on how we could further support this community.\n\nhttps://events.saip.org.za/event/145/contributions/1577/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1577/ END:VEVENT BEGIN:VEVENT SUMMARY:Experimental charge and spin densities studies on perovskite of YT iO 3 through Joint refinement of X-ray and polarized neutron diffraction d ata DTSTART;VALUE=DATE-TIME:20190129T150000Z DTEND;VALUE=DATE-TIME:20190129T151500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1578@events.saip.org.za DESCRIPTION:Speakers: Ariste Bolivard Voufack (Université de Lorraine\, V andœuvre-lès-Nancy\, France)\nThe study and the understanding of both ph ysical and chemical properties of\ninorganic materials remain a perpetual challenge. In the present work\, the modelling\nof charge densities of bot h paramagnetic and ferromagnetic perovskite structure of\nYTiO 3 is undert aken. The structural analysis of this inorganic compound in these two\nmag netic phases showed that the shape of Ti octahedron is irregular expressin g the\ninteractions between electron of Ti atom and O atoms of its environ ment. The charge\ndensity around Ti atom changes significantly between par amagnetic and\nferromagnetic phases. The spin-split multipolar model is us ed in the frame of a joint\nrefinement of X-ray (XRD) and polarization neu tron (PND) diffraction data [1] in\nferromagnetic phase. The experimental distributions of alpha and beta spin electrons\nis obtained and their repr esentation agrees with the orbital ordering suggested by\nprevious work of Ito et al. [2] and Hichikawa et al. [3\, 4] from X-ray magnetic\ndiffract ion (XMD) and PND respectively. Its ferromagnetic order is due to the\npre sence of an unpaired electron localized on Ti atom. The spin density distr ibution\nshows the shape of t 2g orbital for the unpaired electron. Furthe rmore\, the provided\nmodelling of charge density shows a charge depletion around Ti atom towards the O\natoms described by e g orbitals\, meanwhile an accumulation of the density in bisecting\ndirections expresses the t 2 g orbitals. Theoretical calculations based on density\nfunctional theory ( DFT) methods were also carried out and a comparison with these\nresults wi ll be done.\n[1] Deutsch M. et al.\, IUCrJ \, 1\,194—199\, 2014.\n[2] It o M. et al.\, Journal of Physics and Chemistry of Solids\, 65\, 1993—199 7\, 2004.\n[3] Ichikawa H. et al.\, Physica B\, 281\, 482—484\, 2000.\n[ 4] Kibalin I. A. et al.\, Phys. Rev. B 96\, 054426\, 2017.\n\nhttps://even ts.saip.org.za/event/145/contributions/1578/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1578/ END:VEVENT BEGIN:VEVENT SUMMARY:Polymorphism in Molecular Crystals: New and Old Stories DTSTART;VALUE=DATE-TIME:20190130T105500Z DTEND;VALUE=DATE-TIME:20190130T112000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1579@events.saip.org.za DESCRIPTION:Speakers: A Cruz-Cabez (N/A)\nThis contribution highlights som e recent work on polymorphism in molecular crystals. First\, we review the concept of conformational polymorphism [1] and its occurrence in drug com pounds [2]. Conformational polymorphs may differ in properties more signif icantly than packing polymorphs thus they are of special interest in the p harmaceutical industry. \nSecond we study the crystallisation behavior of various model pharmaceuticals such as tolfenamic acid (TA) [3] and p-amin obenzoic acid (pABA) [4]. TA was studied because it has conformational po lymorphs. We found that the two main conformers of TA were continuously in terconverting in solution. Hence\, despite the fact that two conformationa l polymorphs can be obtained from crystallisations\, no links were found b etween solution conformation and crystallisation outcomes. In pABA\, the e ffect of additives on the growth kinetics\, crystal morphologies and ultim ate polymorphic outcome was investigated [4]. Using small amounts of addit ives\, we were able to crystallise the more unusual polymorph of pABA (the beta form).\n\nFinally\, we study the effect of crystal size on the therm odynamic stability of polymorphic systems. We show that milling experiment s always lead to the thermodynamically stable polymorph. However\, the the rmodynamically stable polymorph may change as the size of the crystallites becomes smaller [5]. \n\n[1] A. J. Cruz-Cabeza & J. Bernstein\, Chem. Rev . 2014\, 114\, 2170–2191.\n[2] A. J. Cruz-Cabeza\, S.M. Reutzel-Edens & J. Bernstein\, Chem. Soc. Rev. 2015\, 44\, 8619.\n[3] W. Du\, A. J. Cruz-C abeza\, S. Woutersen\, R. J. Davey & Q. Yin\, Chem. Sci. 2015\, 6\, 3515-3 524.\n[4] J. F.B. Black\, A. J. Cruz-Cabeza\, R. J. Davey\, R.D. Willacy\, A. Yeoh\, Cryst. Growth & Des. 2018\, in press.\n[5] A. M. Belenguer\, G. I. Lampronti\, A. J. Cruz-Cabeza\, C. A. Hunter\, and J. K. M. Sanders\,\ nChemical Science\, 2016\, 7\, 6617.\n\nhttps://events.saip.org.za/event/1 45/contributions/1579/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1579/ END:VEVENT BEGIN:VEVENT SUMMARY:Molecular architectures of essential components the pCW3 DNA trans fer apparatus DTSTART;VALUE=DATE-TIME:20190129T122000Z DTEND;VALUE=DATE-TIME:20190129T124000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1580@events.saip.org.za DESCRIPTION:Speakers: Daouda Traore (Monash University)\nN/A\n\nhttps://ev ents.saip.org.za/event/145/contributions/1580/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1580/ END:VEVENT BEGIN:VEVENT SUMMARY:Science at ALBA : Research highlights\, Socio-economic impacts and insights the AfLS DTSTART;VALUE=DATE-TIME:20190131T110000Z DTEND;VALUE=DATE-TIME:20190131T112500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1581@events.saip.org.za DESCRIPTION:Speakers: Katerina Biscari (N/A)\nTo be added\n\nhttps://event s.saip.org.za/event/145/contributions/1581/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1581/ END:VEVENT BEGIN:VEVENT SUMMARY:Turning liquid active ingredients into crystals DTSTART;VALUE=DATE-TIME:20190130T103000Z DTEND;VALUE=DATE-TIME:20190130T105500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1582@events.saip.org.za DESCRIPTION:Speakers: Alessia Bacchi (N/A)\nWe present a systematic way to embed liquid or volatile molecules inside crystalline materials in order to tune tuning their delivery for medicine or agrochemistry. Liquid or vol atile formulations of active pharmaceutical ingredients (APIs) are intrins ically less stable and durable than solid forms. In fact most drugs and ag rochemicals are manufactured and distributed as crystalline materials\, an d their action involves the delivery of the active molecule by a solubiliz ation process either in the body or on the environment. The poor solubilit y of API or the reverse too high solubility of agrochemicals are problems often encountered in their formulation since these phenomena limit respect ively the bioavailability of the API or the duration of the action of the agrochemical. However some important compounds for the human health or for the environment are liquid at room temperature\; examples are thymol\, eu genol\, carvacrol\, nicotine\, propofol\, and we present a twofold approac h to embed them in crystalline hosts: by cocrystals and by MOFs. The forma tion of co-crystals alters solubility of solid phases\, and is widely inve stigated for pharmaceuticals\, agrochemicals\, pigments\, dyestuffs\, food s\, and explosives. In spite of this extremely high interest towards co-cr ystallization as a tool to alter solubility\, practically no emphasis has been paid to using it as a means to stabilize volatile or labile or liquid products. In this work we trap and stabilize volatile and liquid APIs and agrochemicals in crystalline matrices by engineering suitable co-crystals . These new materials alter the physic state of the active ingredients all owing to expand the phase space accessible to manufacturing and delivery. We also explore the possibility to include liquid APIs inside the pores of suitable designed MOFs (Figure)\, again with the aim of stabilizing their solid state formulation.\n\nhttps://events.saip.org.za/event/145/contribu tions/1582/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1582/ END:VEVENT BEGIN:VEVENT SUMMARY:Science at SESAME : Research highlights\, Socio-economic impacts a nd insights for the AfLS DTSTART;VALUE=DATE-TIME:20190131T115000Z DTEND;VALUE=DATE-TIME:20190131T121500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1583@events.saip.org.za DESCRIPTION:Speakers: Giorgio Paolucci (SESAME)\nScience at SESAME: Resear ch highlights\, Socio-economic impacts and insights for the AfLS\n\nhttps: //events.saip.org.za/event/145/contributions/1583/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1583/ END:VEVENT BEGIN:VEVENT SUMMARY:Combining photocrystallography and infrared spectroscopy for the s tudy of nitric oxide and nitrite linkage isomers DTSTART;VALUE=DATE-TIME:20190130T120000Z DTEND;VALUE=DATE-TIME:20190130T121500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1584@events.saip.org.za DESCRIPTION:Speakers: Dominik Schaniel (Université de Lorraine\, CNRS\, C RM2\, Nancy\, France)\nIn the last few years we have studied a number of c omplexes containing the photoswitchable\nligands NO and NO2 [1-4]. On the examples of [RuX(NO)2(PR3)2]BF4 (PR3 = PPh3\, PCyp3\,\nPcy3\; X=Cl\, Br\, I) and [Rh(NO)(NO2)2(But\n\n2PH)2] we will demonstrate how the combination of\nphotocrystallography and infrared spectroscopy allows for structural characterization of the\nphotoinduced linkage isomers (PLI) as well as ded ucing a general scheme for their generation.\nFurthermore\, we will discus s the possibility of selectively addressing one or the other ligand\nfor g eneration of a NO or NO2 linkage isomer by choosing appropriate excitation wavelengths.\n\nhttps://events.saip.org.za/event/145/contributions/1584/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1584/ END:VEVENT BEGIN:VEVENT SUMMARY:Virulence factors of Listeria monocytogenes and their host recepto r interactions DTSTART;VALUE=DATE-TIME:20190129T112000Z DTEND;VALUE=DATE-TIME:20190129T114000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1586@events.saip.org.za DESCRIPTION:Speakers: Wolf-Dieter Schubert (University of Pretoria)\nVirul ence factors of Listeria monocytogenes and their host receptor interaction s\n\nhttps://events.saip.org.za/event/145/contributions/1586/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1586/ END:VEVENT BEGIN:VEVENT SUMMARY:Review of SA associate membership of the European Synchrotron Radi ation Facility (ESRF) DTSTART;VALUE=DATE-TIME:20190201T104000Z DTEND;VALUE=DATE-TIME:20190201T105000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1625@events.saip.org.za DESCRIPTION:Speakers: Tshepo Ntsoane (Necsa)\nOver the last decade\, the n umber of South African users accessing synchrotron facilities around the w orld has been steadily increasing with a significant fraction of the incre ase being early career scientists and students. In 2013\, following a requ est by the synchrotron community\, the South African government entered in to a 5-year medium-term scientific relationship with the European Synchrot ron Radiation Facility (ESRF). The contract was aimed at facilitating supp ort for SA’s Users assessing the ESRF synchrotron facilities for scienti fic experiments. \n\nThis talk will review the SA synchrotron-based activi ties undertaken over that period\; this will include examples of the succe ss achieved\, the science carried out as well as beam time uptake in terms of the beam time usage. Areas of growth in terms of Users and disciplines will also be highlighted. Limitation of membership benefits emanating fro m the structure of the association will be discussed and alternative scena rio that can assist in maximizing other membership benefits will be presen ted. Lastly the status of the contract\; outlining possible role of young people at ESRF during the upgrade period will be presented\n\nhttps://even ts.saip.org.za/event/145/contributions/1625/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1625/ END:VEVENT BEGIN:VEVENT SUMMARY:Crystallization of membrane transport proteins in Lipidic Cubic Me sophase (LCP) aided by an engineered Green Fluorescent Protein Thermal Shi ft Screen (GFP-TS) DTSTART;VALUE=DATE-TIME:20190129T120000Z DTEND;VALUE=DATE-TIME:20190129T122000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1587@events.saip.org.za DESCRIPTION:Speakers: Emmanuel Nji (Centre for Biomembrane Research\, Depa rtment of Biochemistry and Biophysics\, Stockholm)\nMembrane protein cryst als grown by in meso or the lipidic cubic phase (LCP) method generally pro duce higher resolution structures\, as they have a lower solvent content ( type I crystals) than those grown by traditional vapour-diffusion crystall ization (type II crystals). To grow LCP crystals of membrane proteins with the synthetic lipid monoolein\, the purified membrane protein solution is mixed with the molten monoolein in a weight ratio of 2:3. It can be very challenging to grow LCP crystals of membrane proteins\, however\, and whil e it is generally thought to be a fairly mild environment\, the stabilitie s of different membrane proteins have not been extensively compared.\nWe e ngineered a Green Fluorescent Protein Thermal Shift Screen (GFP-TS) and us e it to identify specific lipid for the bacteria sodium proton exchanger ( NhaA) and also\, specific ligand for the plant homologue of the human CMPs ialic acid/CMP exchanger (SLC35A1). The former was crystallized and the st ructure solved by LCP in the presence of its specific lipid while the latt er in the presence of its specific ligand at 2.3 and 2.8 Å respectively. No detectable crystal was obtained in the absence of either the lipid or l igand after extensive crystallization trials. The GFP-TS method should pro ve useful for screening lipid additives and small molecules not only to st abilize membrane proteins for structural determination by X-ray crystallog raphy and single particle Cryo-EM but also to identify drug candidates of these medically relevant membrane proteins.\n\nhttps://events.saip.org.za/ event/145/contributions/1587/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1587/ END:VEVENT BEGIN:VEVENT SUMMARY:Trypanosoma brucei polyamine biosynthesis enzyme structures provid e information about novel metabolism and regulation DTSTART;VALUE=DATE-TIME:20190130T170000Z DTEND;VALUE=DATE-TIME:20190130T172000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1588@events.saip.org.za DESCRIPTION:Speakers: Tomchick Tomchick (UT Southwestern Medical Center\, USA)\nTrypanosoma brucei is a neglected tropical disease endemic to Africa . We structurally characterize enzymes in biosynthetic pathways of trypano somatids to potentially exploit them as targets for development of anti-pr oliferative agents. The polyamine spermidine is essential for post-transla tional hypusine modification of eukaryotic initiation factor 5A (eIF5A)\, which is catalyzed by deoxyhypusine synthase (TbDHS). In trypanosomatids\, deoxyhypusine synthase (DHS) activity is dependent on heterotetramer form ation between two paralogs\, DHSc and DHSp\, both with minimal activity on their own due to missing catalytic residues. We determined the X-ray stru cture of TbDHS showing a single functional shared active site is formed at the DHSc/DHSp heterodimer interface\, with deficiencies in one subunit co mplemented by the other. Each heterodimer contains two NAD+ binding sites\ , one housed in the functional catalytic site and the second bound in a re mnant dead site that lacks key catalytic residues. Differences between try panosomatid and human DHS that could be exploited for drug discovery were identified.\n\nCatalytically inactive enzyme paralogs occur in many genome s\, including the trypanosomatids. Some regulate their active counterparts \, but the structural principles of this regulation remain largely unknown . We report X-ray structures of Trypanosoma brucei S-adenosylmethionine de carboxylase alone and in functional complex with its catalytically dead pa ralogous partner\, prozyme. We show monomeric TbAdoMetDC is inactive becau se of autoinhibition by its N-terminal sequence. Heterodimerization with p rozyme displaces this sequence from the active site through a complex mech anism involving a cis-to-trans proline isomerization\, reorganization of a beta-sheet\, and insertion of the N-terminal alpha-helix into the heterod imer interface\, leading to enzyme activation. These studies elucidate an allosteric mechanism in an enzyme and a plausible scheme by which such com plex cooperativity evolved.\n\nhttps://events.saip.org.za/event/145/contri butions/1588/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1588/ END:VEVENT BEGIN:VEVENT SUMMARY:A possible Pan-African Consortium Membership of an International S ynchrotron DTSTART;VALUE=DATE-TIME:20190201T105000Z DTEND;VALUE=DATE-TIME:20190201T110500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1589@events.saip.org.za DESCRIPTION:Speakers: Prosper NGABONZIZA (Max Planck Institute for Solid S tate Research)\nExplore possible partnership with other African Countries to get Full Member Status\n\nhttps://events.saip.org.za/event/145/contribu tions/1589/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1589/ END:VEVENT BEGIN:VEVENT SUMMARY:SYNCHROTRON RADIATION STUDIES of STRUCTURE and REACTIVITY in CATAL YTIC and ENERGY MATERIALS DTSTART;VALUE=DATE-TIME:20190131T121500Z DTEND;VALUE=DATE-TIME:20190131T123000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1590@events.saip.org.za DESCRIPTION:Speakers: Catlow Richard (Richard Catlow\; Department of Chemi stry\, University College London\; School of Chemistry\, Cardiff Universit y\; UK Catalysis Hub\, Research Complex at Harwell\, UK)\nWe will describe how the concerted use of synchrotron radiation methods with modelling tec hniques can yield unique information on structures\, dynamics and mechanis m in a range of catalytic and energy materials. Our discussion will concen trate on the the structures and reactivities of oxide supported nano-parti culate catalysts\, including insights in the re-structuring of nano-partic les during catalytic reactions.\nWe will also consider areas of industria l catalytic science where the synergistic use of modelling with X-ray tech niques could be fruitfully applied.\n\nhttps://events.saip.org.za/event/14 5/contributions/1590/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1590/ END:VEVENT BEGIN:VEVENT SUMMARY:XTech-SD: a unique regional training initiative within the Sèmè City hub in Benin DTSTART;VALUE=DATE-TIME:20190129T110000Z DTEND;VALUE=DATE-TIME:20190129T113000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1591@events.saip.org.za DESCRIPTION:Speakers: Thierry d'Almeida (CEA France)\nX-ray experimental a nd analysis techniques are indispensable tools for addressing major challe nges in many fields\, including health\, energy\, agriculture and environm ent. Hence\, building a Light Source Facility somewhere in Africa in the n ear future is a key priority that is being addressed through the efforts o f both the African Light Source Foundation and the Light Source for Africa \, the Americas\, Asia and the Middle east Project (LAAAMP).\nBesides thes e endeavors\, a training program dedicated to X-Ray Techniques for Sustain able Development (XTech-SD) is being established within the Sèmè City hu b\, one of Benin Government’s flagship projects\, which aims to create a world-class knowledge and innovation center in Africa. The overall object ive of XTech-SD is to endow the local and regional scientific communities with technical skills that will allow them to use X ray techniques as tool s for solving specific critical socioeconomic issues. Also\, this program is expected to train a breeding-ground of experts that will animate and co ntribute to the AfLS roadmap.\nWe report the current status of the XTech-S D initiative and discuss various scientific\, technical and organizational aspects of the program.\n\nhttps://events.saip.org.za/event/145/contribut ions/1591/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1591/ END:VEVENT BEGIN:VEVENT SUMMARY:Panel Discussion : AfLS2 Workshop 2 : African Consortia: Towards t he AfLS : Learning from other LSs\, partnering with other LSs DTSTART;VALUE=DATE-TIME:20190128T170000Z DTEND;VALUE=DATE-TIME:20190128T173000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1592@events.saip.org.za DESCRIPTION:Speakers: Lawrence Norris (National Society of Black Physicist s)\nPanel Discussion\n\nhttps://events.saip.org.za/event/145/contributions /1592/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1592/ END:VEVENT BEGIN:VEVENT SUMMARY:Structure-guided Fragment-based Drug Discovery for Cancer and Tub erculosis: Fighting the Emergence of Resistance DTSTART;VALUE=DATE-TIME:20190130T090000Z DTEND;VALUE=DATE-TIME:20190130T100000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1593@events.saip.org.za DESCRIPTION:Speakers: Tom Blundell (Cambridge University)\nKnowledge deriv ed from genome sequences of humans and pathogens has the potential to acce lerate diagnosis\, prognosis and cure of disease. We are moving quickly in to an era of precision medicine\, not only in familial diseases where a mu tation in a human gene is important\, but also for understanding somatic m utations in cancer. Equally important\, the genome sequences of pathogens \, for example in tuberculosis or leprosy\, can give clues about the choic e of existing drugs\, repurposing of others\, and the design of new ones t o combat the increasing occurrence of drug resistance. High-throughput X-r ay crystallography using synchrotron sources plays a major role in assessi ng the druggability of candidate targets identified from the genome sequen ces.\n\nOne approach is to exploit state-of-the-art methods to bring new d rugs for different targets to the market\, but this will be difficult to f inance if patient populations are small. Structure-guided fragment-based s creening techniques have proved effective in lead discovery not only for c lassical enzyme targets but also for less “druggable” targets such as protein-protein interfaces. Initial screening involves small fragments wit h very low\, often millimolar affinities\, and biophysical methods includi ng X-ray crystallography are used to explore chemical space of potential l igands. The approach involves a fast initial screening of a library of aro und 1000 compounds\, followed by a validation step involving more rigorous use of related methods to define three-dimensional structure\, kinetics a nd thermodynamics of fragment binding. The use of high throughput approach es\, with X-ray synchrotron sources playing a major role\, does not end th ere\, as it becomes a rapid technique to guide the elaboration of the frag ments into larger molecular weight lead compounds. I will discuss progress in using these approaches for targets in cancer and in mycobacteria tube rculosis\, abscessus and leprae infections\, focusing on the applications of X-ray crystallography. I will include discussion of collaborations with the Institute of Infectious Disease & Molecular Medicine in Cape Town\, S outh Africa.\n\nI will also review our computational approaches using both statistical potentials (SDM) and machine learning methods (mCSM) for unde rstanding mechanisms of drug resistance. These are dependent X-ray crystal lographic and comparative modeling to define structures. We have demonstra ted that resistance does not only arise from direct interference of the re sistance mutation to drug binding but can also result allosteric mechanism s\, often modifying target interactions with other proteins. This has led to new ideas about repurposing and redesigning drugs.\n\nhttps://events.sa ip.org.za/event/145/contributions/1593/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1593/ END:VEVENT BEGIN:VEVENT SUMMARY:Grenoble Innovation Campus: The role and impact of ESRF Synchrotr on DTSTART;VALUE=DATE-TIME:20190128T103000Z DTEND;VALUE=DATE-TIME:20190128T110000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1594@events.saip.org.za DESCRIPTION:Speakers: Edward Mitchell (ESRF)\nTBA\n\nhttps://events.saip.o rg.za/event/145/contributions/1594/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryetey Hall URL:https://events.saip.org.za/event/145/contributions/1594/ END:VEVENT BEGIN:VEVENT SUMMARY:Panel Discussion : AfLS2 Workshop 1 : Towards the AfLS: Learning f rom other LSs\, partnering with other LSs DTSTART;VALUE=DATE-TIME:20190128T123000Z DTEND;VALUE=DATE-TIME:20190128T133000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1595@events.saip.org.za DESCRIPTION:Speakers: Prosper NGABONZIZA (Max Planck Institute for Solid S tate Research)\nPanel Discussion\n\nhttps://events.saip.org.za/event/145/c ontributions/1595/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryetey Hall URL:https://events.saip.org.za/event/145/contributions/1595/ END:VEVENT BEGIN:VEVENT SUMMARY:A structural biology approach for the discovery of aldehyde dehydr ogenases 1A isozymes specific inhibitors DTSTART;VALUE=DATE-TIME:20190129T124000Z DTEND;VALUE=DATE-TIME:20190129T130000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1636@events.saip.org.za DESCRIPTION:Speakers: Menico Rizzi (Università Piemonte Orientale)\nThe m ore than a century years old NAD(P)H still triggers a wealth of investigat ions that mainly focus on its role in signalling and aim to develop novel drugs that interfere with specific aspects of such a process in different pathological conditions. However\, the cofactor plays a key\, essential an d long studied role as a redox molecule in central metabolism\, a source o f robust drug targets for the treatment of several pathologies\, ranging f rom infective diseases to cancer. In this context\, NAD(P)H dependent dehy drogenases are amongst the most studied and exploited enzymatic drug targe ts. Independently on the specific disease\, a major issue in targeting NAD (P)H dependent dehydrogenases is represented by the selectivity of drug ac tion. Within this context\, we show that potent hit/lead compounds selecti vely targeting different isozymes of the human aldehyde dehydrogenases 1A sub-family can be identified for the development of novel therapeutic inte rventions to fight cancer.\n\nhttps://events.saip.org.za/event/145/contrib utions/1636/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1636/ END:VEVENT BEGIN:VEVENT SUMMARY:Advanced diffraction techniques for operando and ex-situ studies o f real systems DTSTART;VALUE=DATE-TIME:20190201T090000Z DTEND;VALUE=DATE-TIME:20190201T100000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1596@events.saip.org.za DESCRIPTION:Speakers: Gavin Vaughan (M/Europe)\nThe well-established diffr action techniques of classical single crystal and powder diffraction have been hugely influential in the study of materials structure and of functio nal relationships to that structure. However\, the characterization chall enge for materials scientists is always to bring the conditions of our exp eriments as close as possible to the real conditions under which the syste ms we study operate. To that end\, it is necessary to study samples of phy sical and chemical interest in the state in which they function. To do so\ , we must probe the time and length scales characteristic of the propertie s of interest\, on non-optimized samples in terms of crystallinity and mor phology\, and to do so in an environment as close as possible to that unde r which the process under study takes place in a real setting.\nWe will de scribe the range of techniques which have been recently developed to chara cterise the atomic-level structure of far-from ideal samples such as amorp hous\, poorly crystalline or micron scale samples. We will also describe t he use of tomographic approaches to crystallographically study the compone nts of working systems.\nThis technique\, X-Ray Diffraction Computed Tomog raphy (XRD-CT) offers much richer information on the chemical and microstr uctural characteristics of the sample than absorption or phase-contrast to mography\, as each reconstructed voxel contains not a scalar quantity but an entire diffraction pattern. Recent technical advancements in X-ray opti cs and high-speed/high-efficiency photon counting detectors have greatly r educed data collection times\, allowing the study of real working devices under operando conditions with three-dimensional resolution of several mic rometres. Furthermore\, implementation of pair distribution function metho ds allow even amorphous samples to be characterized in this way.\nWe will present the principles of the methods used\, drawing from recent examples of samples measured within operating catalytic reactors\, batteries\, and other devices.\n\nhttps://events.saip.org.za/event/145/contributions/1596/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1596/ END:VEVENT BEGIN:VEVENT SUMMARY:Latest developments in laboratory SAXS/WAXS instruments DTSTART;VALUE=DATE-TIME:20190128T153000Z DTEND;VALUE=DATE-TIME:20190128T160000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1597@events.saip.org.za DESCRIPTION:Speakers: Frederic Bossan (Xenocs)\nXenocs provides complete s olutions for characterizing the nanostructure and morphology of materials. The product portfolio of the company includes innovative high-performance instruments that combine Small and Wide Angle X-ray Scattering techniques (SAXS/WAXS) for soft matter\, nanomaterials\, or polymers characterizatio n. Founded as a spinoff company from the Institute Laue Langevin\, in Gren oble\, France\, Xenocs supplies its solutions to leading research and deve lopment institutions around the world. On January 2017\, Xenocs acquired t he Danish company SAXSLAB Aps\, recognized leader in high end Small Angle X-ray Scattering laboratory equipment\, and its subsidiary SAXSLAB US Inc. based in Northampton\, MA\, USA.\n\nIn parallel to the advent of dedicate d synchrotron radiation sources and beamlines\, several breakthroughs have been accomplished for laboratory analytical x-ray instrumentation and in particular for Small Angle X-ray Scattering (SAXS) instrumentation. Breakt hroughs include X-ray micro-focus sources with aspheric multilayer coated optics\, scatterless collimation [1]\, sample environment\, software and h ybrid pixel photon counting detectors as well as instrument design with fo r example multiple source energy capability [2].\n\nToday\, these technolo gies combine to provide in-laboratory SAXS instruments\, with a performanc e comparable to that previously achieved only at synchrotrons. Flexible in strument designs provide simultaneous measurement of Wide Angle X-ray Scat tering (WAXS) signal in various sample forms (including thin film) and exp erimental conditions. The state-of-the-art performance opens the way for a wide range of applications\, including scattering from soft matter. Perfo rmance and possibilities will be illustrated through a few application exa mples such as characterization of highly diluted macromolecules or in-situ dynamic studies of complex soft materials.\n\nThis presentation will revi ew the latest developments of Xenocs SAXS/WAXS instruments and a special e mphasis will be done on how well they complement large research facilities through customer cases.\n\n[1] Y.Li et al.\, J. Appl. Cryst.\, 2008\, 41\ n[2] S. Koppoju et al.\, J. Appl. Cryst.\, 2015\, 48\n\nhttps://events.sai p.org.za/event/145/contributions/1597/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1597/ END:VEVENT BEGIN:VEVENT SUMMARY:Cryo EM as feeder infrastructure in Regional Facilities DTSTART;VALUE=DATE-TIME:20190128T143000Z DTEND;VALUE=DATE-TIME:20190128T150000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1598@events.saip.org.za DESCRIPTION:Speakers: Mike Mike Lawrence (walter eliza hall institute of m edical research)\nCryo EM as feeder infrastructure in Regional Facilities\ n\nhttps://events.saip.org.za/event/145/contributions/1598/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1598/ END:VEVENT BEGIN:VEVENT SUMMARY:The impact of CryoEM and the centre for cryoEM at Diamond DTSTART;VALUE=DATE-TIME:20190129T123000Z DTEND;VALUE=DATE-TIME:20190129T130000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1599@events.saip.org.za DESCRIPTION:Speakers: Ralf Flaig (Diamond Light Source)\nCryoEM is now a m ajor driver of structural biology\, especially for complex systems. It is possible to obtain structures at better than 2 A resolution in favourable cases\, and also possible to obtain 3 A structures of complexes larger tha n 100 MDa in mass. Beyond this\, new methods are emerging which allow lowe r resolution visualisation of complex structures within living cells. Mos t structural biology labs now want to use cryoEM\, especially alongside X- ray crystallography as one of their main techniques. However the equipment remains very expensive and so the UK decided to establish a central facil ity at Diamond – eBIC. eBIC has been functional for three years and has grown enormously. eBIC now houses five high-end Krios microscopes\, inclu ding one dedicated to industry use and run as a partnership with Thermo Fi sher. Despite the increase in provision there is still oversubscription fo r microscope time. eBIC is completely embedded within Diamond and access p rovided through the normal Diamond peer review route\, with most access pr ovided through the Block Allocation Group model\, which was originally dev eloped at the ESRF for macromolecular crystallography and is now widely us ed. The output has been outstanding\, as judged by ~70 high quality peer r eviewed publications. The presentation will outline the current situation and future potential for cryoEM facilities.\n\nhttps://events.saip.org.za/ event/145/contributions/1599/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1599/ END:VEVENT BEGIN:VEVENT SUMMARY:Bioscience Highlights from South Africa DTSTART;VALUE=DATE-TIME:20190129T143000Z DTEND;VALUE=DATE-TIME:20190129T150000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1600@events.saip.org.za DESCRIPTION:Speakers: Wolf-Dieter Schubert (University of Pretoria)\nRevie w of Bioscience highlights from Africa and the START programme from a Bios cience perspective\n\nhttps://events.saip.org.za/event/145/contributions/1 600/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1600/ END:VEVENT BEGIN:VEVENT SUMMARY:The European Synchrotron Radiation Facility - 30 years of Science DTSTART;VALUE=DATE-TIME:20190131T103000Z DTEND;VALUE=DATE-TIME:20190131T110000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1601@events.saip.org.za DESCRIPTION:Speakers: Francesco Sette (European Synchrotron Radiation Faci lity (ESRF))\nI will review the Operation of the ESRF during its last 30 y ears\, highlighting its role in constructing the international community o f synchrotron users\n\nhttps://events.saip.org.za/event/145/contributions/ 1601/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1601/ END:VEVENT BEGIN:VEVENT SUMMARY:Structural biology @Elettra: an integrated approach to DNA replica tion and repair DTSTART;VALUE=DATE-TIME:20190129T110000Z DTEND;VALUE=DATE-TIME:20190129T112000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1603@events.saip.org.za DESCRIPTION:Speakers: Silvia Onesti (N/A)\nStructural biology @Elettra: an integrated approach to DNA replication and repair\n\nhttps://events.saip. org.za/event/145/contributions/1603/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1603/ END:VEVENT BEGIN:VEVENT SUMMARY:Deliberations from PCCr2 and an African Light Source DTSTART;VALUE=DATE-TIME:20190201T140000Z DTEND;VALUE=DATE-TIME:20190201T141500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1604@events.saip.org.za DESCRIPTION:Speakers: Robert Kingsford-Adaboh (University of Ghana)\nThe P CCr2 Conference is now also reaching its end.\nFor a many years\, includin g more recently in the planning stages of PCCr2\, there was a vision of a large scale infrastructure for Africa. Indeed sessions with this focus wer e present in the PCCr2 early programme. It was therefore natural to partne r with the AfLS2 Conference. At PCCr2\, there has been an excellent spread of contributions\, using both lab facilities and also large scale infrast ructures. This has enabled the PCCr community to develop its thinking furt her and to make well founded and deep contributions to this strategic sess ion.\n\nhttps://events.saip.org.za/event/145/contributions/1604/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1604/ END:VEVENT BEGIN:VEVENT SUMMARY:Synchrotron x-rays: helping build communities and get drugs to mar ket DTSTART;VALUE=DATE-TIME:20190130T140000Z DTEND;VALUE=DATE-TIME:20190130T143000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1654@events.saip.org.za DESCRIPTION:Speakers: Simon Billinge (Columbia University)\nShared facilit ies\, such as synchrotron sources\, are important and dynamic hubs for sci entific collaboration and innovation. They also proved state of the art c apabilites that can catapault science forwards and provide a focal point i n scientific communities\, as well as providing important capabilities for industry to develop new products. I will describe how we have used synch rotrons to advance our understanding of amorphous and nanostructure pharma ceuticals\, that led to important insights that can help drug companies so lve the solubility problem and bring to market new drug products.\n\nhttps ://events.saip.org.za/event/145/contributions/1654/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1654/ END:VEVENT BEGIN:VEVENT SUMMARY:Pannel Discussion : Realising the Pan African Synchrotron II DTSTART;VALUE=DATE-TIME:20190201T153500Z DTEND;VALUE=DATE-TIME:20190201T160000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1606@events.saip.org.za DESCRIPTION:Pannel discussion \nbased on a panel consisting of a \nChair a nd \nPanelists from the Key Note Speakers\n\nhttps://events.saip.org.za/ev ent/145/contributions/1606/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1606/ END:VEVENT BEGIN:VEVENT SUMMARY:Political and Strategic Outcomes planned for AfLS2 DTSTART;VALUE=DATE-TIME:20190201T103000Z DTEND;VALUE=DATE-TIME:20190201T104000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1608@events.saip.org.za DESCRIPTION:Speakers: Simon Connell (University of Johannesburg)\nThe Afri can Light Source Foundation and the African Light Source Steering Committe e has been active in unifying a broad global collaboration of stakeholders towards the common goal of a Light Source in Africa. The stakeholders are many\, and their contributions have been given profile and recognised in this Conference. In addition\, this conference has heard about the vast sp read and also the excellence of research by African scientists in collabor ation with their colleagues globally. Many of the research programmes are of great impact\, especially for Africa. The user base and the involvement of young people has grown dramatically. There has been a growth also in t he local infrastructure and institutions. There is an increasing profile o f the programme scientifically and politically. \nWhere to from here ?\nTh e AfLS2 Conference has targeted specific outcomes which we will now focus on to produce the documents summarising conference outcomes. We look forwa rd to the general progress of the Roadmap\, but specifically\, we would li ke to see a Pan African ethos for the African Light Source establish itsel f very strongly. We would like to see Regional Facilities established and supported strongly by local governments as well as our international stake holders. We would like to see sustainable and deep regular Schools and Use r Meetings. We would like to see longer term trainings and residences of A frican Scientists at International facilities. We would like to see severa l African Beam Lines at major international facilities\, focussing on our strengths\, such as heritage research\, the biosciences and all sciences r elated to materials and resources. We would like to see African Consortia membership of these International Facilities.\nUltimately this will streng then the discussions towards an African Light Source itself.\n\nhttps://ev ents.saip.org.za/event/145/contributions/1608/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1608/ END:VEVENT BEGIN:VEVENT SUMMARY:Pannel Discussion : Realising the Pan African Synchrotron I DTSTART;VALUE=DATE-TIME:20190201T120000Z DTEND;VALUE=DATE-TIME:20190201T123000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1609@events.saip.org.za DESCRIPTION:Speakers: Felix Dapare Dakora (African Academy of Science)\nPa nel discussion\, based on a panel consisting of a Chair and Panelists from the Key Note Speakers\n\nhttps://events.saip.org.za/event/145/contributio ns/1609/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1609/ END:VEVENT BEGIN:VEVENT SUMMARY:Single crystal to single crystal transformations in Co(II)-tricarb oxylate metal-organic frameworks. DTSTART;VALUE=DATE-TIME:20190130T114500Z DTEND;VALUE=DATE-TIME:20190130T120000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1610@events.saip.org.za DESCRIPTION:Speakers: Christelle Dzesse Tekouo (University of Buea\, Depar tment of Chemistry)\nMetal-organic frameworks (MOFs) are an emerging class of crystalline materials made by connecting a metal ion or cluster to pol ytypic organic linkers. They have a wide range of potential applications in gas storage\, catalysis\, drug delivery\, sensing\, separation\, and ma gnetism.3\,4\nSingle crystal to single crystal (SC-SC) transformation is a phenomenon where significant changes in the crystal structure occur in th e solid state without destroying the integrity of the crystal such that it can still be analyzed by means of X-ray diffraction. Single crystal trans formations are important for the development of new and technologically us eful materials including devices and sensors. \nIn this work\, various MOF s including {Co3(µ3-O)(BTC)2(H2O)4.5(EtOH)0.5(DMF)2}n (1)\, {Co1.5(µ3-O)(BTB)(H2O)3.5(DMF)1.5}n (2)\, [Co3(µ3-O)(BTB)2(OH2)3]( DMF)2(H2O)13.2(3)\, [Co1.5(µ-OH)0.5BT B(OH2)(DMF)0.5](DMF)0.5(H2O)6 (4) and Co0.25C6.75H4.5N0.25O\, (4’)\, (BT C= 1\,3\,5-benzenetricarboxylate\, BTB=4\,4’\,4”-benzene-1\,3\,5-triyl trisbenzoate\, DMF= N\,N-dimethylformamide\, EtOH=ethanol) were synthesize d with ethanol and DMF using solvothermal methods. They were fully charac terized using X-ray diffraction methods\, infrared spectroscopy\, elementa l analysis and thermal methods.\n X-ray analysis reveals that (1) crysta llizes in the orthorhombic system with space group of Iba2\, while (2)\, ( 3) and (4) crystallize in the orthorhombic system\, space group Pnma. (4 ’) crystallizes in the cubic system\, space group Pm-3n. The structures of these MOFs have been elucidated and their applications were investigate d.\n\nhttps://events.saip.org.za/event/145/contributions/1610/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1610/ END:VEVENT BEGIN:VEVENT SUMMARY:Model membrane systems to elucidate cell-membrane processes: from signalling proteins to extracellular vesicles interaction. DTSTART;VALUE=DATE-TIME:20190130T120000Z DTEND;VALUE=DATE-TIME:20190130T121500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1624@events.saip.org.za DESCRIPTION:Speakers: Loredana Casalis (Elettra Sincrotrone Trieste)\nCell signalling\, strongly involves plasma cell membranes\, is at the basis of any cell communication process: errors in signalling interactions cause t he development of diseases. The number of complex and dynamical interactio ns between the molecules involved is huge. Therefore model systems are req uired to reduce such complexity.\n\nIn order to mimic lipid and protein or ganization of cellular membranes\, we have developed artificial lipid bila yers that simulate the organization of lipid rafts\, functional microdomai ns that act as signalling platforms. These systems are either planar\, sup ported lipid bilayers\, or lipid vesicles. We use here atomic force micros copy (AFM)\, a powerful tool to study the morphology of macromolecular ass embling and molecular interactions in physiological environment\, compleme nted with x-ray and neutron scattering techniques (SAXS\, SANS) and infrar ed spectroscopy\, to study the interaction of artificial lipid membranes w ith alpha synuclein aggregates and extracellular vesicles (EVs) produced i n disease conditions. Alpha synuclein is the main protein of Parkinson’s disease (PD). The key hallmark of the pathology is the aberrant misfoldin g and aggregation of this presynaptic protein\, which culminates in\nthe f ormation of amyloid fibrils. We demonstrated the ability of iron to induce aggregation of the protein and a functional change of its binding to the membrane that might be associated with the disease. Then\, we studied the interaction of EVs extracted from healthy and diseased cell lines\, with m odel membranes systems. EVs are nanometer-sized cell-derived vesicles ensu ring transport of molecules between cells and throughout the body\, optima l candidates as therapeutic agents in immune therapy\, vaccination\, regen erative medicine\, and drug delivery. The characterization of biophysical and biochemical properties of EVs and of their interaction with the membra ne of recipient cells is fundamental to assess their role. AFM and scatter ing\nmeasurements indicate a strong interaction of EVs with artificial ves icles mimicking lipid rafts pointing out the importance of rafts-like stru cture in the uptake processes.\n\nhttps://events.saip.org.za/event/145/con tributions/1624/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1624/ END:VEVENT BEGIN:VEVENT SUMMARY:X-ray diffraction using the Synchrotron light for molecular materi als DTSTART;VALUE=DATE-TIME:20190129T140000Z DTEND;VALUE=DATE-TIME:20190129T143000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1611@events.saip.org.za DESCRIPTION:Speakers: Pierre Fertey (SOLEIL)\nX-ray scattering is well kno wn as a powerful and relevant technique to probe the structural properties of matter. While X-ray diffraction techniques are widely used in laborato ries\, the specifics of the synchrotron light make it a valuable tool for the most difficult cases. For examples\, the high brightness of the source allows the study of very small single crystals or/and with low diffractin g power. Parralelism of the beam gives access to the ultimate resolution i n powder diagrams. The tunability of the wavelength allows to change the c ontrast between adjacent elements in the periodic table (resonant diffract ion). The pulsed nature of the synchrotron light benefits structural dynam ics studies down to the ps time scale. Furthermore\, new diffraction techn iques using the coherent property of the beam are emerging tools to probe the structural strain and stress at the nanoscale.\nThe CRISTAL beamline a t synchrotron SOLEIL is a dedicated beamline to X-ray diffraction [1]. It offers its users a wide range of diffraction techniques for probing the st ructural properties of matter at different spatial and temporal scales\, p ossibly in non-ambient conditions. In particular\, molecular materials are extensively studied using the different techniques available at the beaml ine\, by a very wide diversity of scientific communities\, to answer all k inds of questions concerning the analysis of the structural properties of this kind materials. \nAmong the accessible techniques\, high angular and/ or spatial resolutions (ab initio powder structure\, electronic densities\ , incommensurate crystals\, quasi-crystals)\, determination of the pair di stribution function\, anomalous diffraction\, grazing incidence diffractio n are available in non-ambient conditions\, thanks to the development of v arious (unique) sample environments\, giving access\, for example\, to the structural contributions during phase transitions.\nCoherent diffraction imaging techniques (Bragg coherent diffraction\, ptychography) are also pr oposed\, to map the deformations\, stress states of micro/nano objects. St ructural dynamics can also be tackled over a very large time scale: the te mporal resolution extending from the millisecond to the sub-picosecond. In situ measurements\, operando (e.g. battery)\, pump-probe experiments (e.g . photo-induced excitations) are among the techniques used to probe the dy namical aspects of the structural properties.\nTherefore\, in this talk\, several examples illustrating the benefit of the synchrotron light for the structural characterization of molecular materials will be addressed\, us ing different techniques such as high resolution powder diffraction\, pair distribution function analysis\, resonnant diffraction\, diffraction unde r extreme conditions\, coherent diffraction or time-resolved diffraction.\ n\nhttps://events.saip.org.za/event/145/contributions/1611/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1611/ END:VEVENT BEGIN:VEVENT SUMMARY:Atoms in Motion: Creating and Characterizing Dynamic Crystalline M aterials DTSTART;VALUE=DATE-TIME:20190129T151500Z DTEND;VALUE=DATE-TIME:20190129T154500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1612@events.saip.org.za DESCRIPTION:Speakers: Jason Benedict (University of Buffalo)\nAtoms in Mot ion: Creating and Characterizing Dynamic Crystalline Materials\n\nhttps:// events.saip.org.za/event/145/contributions/1612/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1612/ END:VEVENT BEGIN:VEVENT SUMMARY:The case for Industry involvement in Light Sources DTSTART;VALUE=DATE-TIME:20190201T110500Z DTEND;VALUE=DATE-TIME:20190201T112500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1613@events.saip.org.za DESCRIPTION:Speakers: Edward Mitchell (ESRF)\nSynchrotron light sources ar guably the means of our age for the ultimate characterisation of materials : such facilities provide the ability to visualise the atomic\, nano-\, an d macro-structure of a huge range of materials and living matter\, often u nder processing or end-use conditions and in real time. This capability le nds itself to an equally wide range of industrial R&D problems which\, in particular\, have been adopted by the healthcare industry. Light sources a re also heavy demanders and developers of innovative advanced instrumentat ion technology such as detectors\, precision mechanics and sample environm ents providing technology spill-over\, transfer and co-development opportu nities.\n\nMoreover\, in Europe and worldwide\, funding agencies are reque sting and demanding a stronger economic return from the significant public investments made in such research facilities and this is resulting in a g radual but firm pressure for stronger interactions with industry. In this context\, new business models are springing to life\, with more partnershi ps\, more services\, and nimble small start-ups bridging the gap between t he research infrastructure and the commercially driven industry world. \n\ nThis presentation will succinctly outline the strategies being deployed a nd the ongoing challenges of working with industry being seen at the Europ ean Synchrotron Radiation Facility (ESRF)\, based in Grenoble France. The talk will look to both the current developments and future possibilities o f business\, as well as review examples of partnerships between academic a nd industry.\n\nhttps://events.saip.org.za/event/145/contributions/1613/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1613/ END:VEVENT BEGIN:VEVENT SUMMARY:SESAME and the AfLS Roadmap DTSTART;VALUE=DATE-TIME:20190201T151000Z DTEND;VALUE=DATE-TIME:20190201T152000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1614@events.saip.org.za DESCRIPTION:Speakers: Giorgio Paolucci (SESAME)\nhttps://events.saip.org.z a/event/145/contributions/1614/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1614/ END:VEVENT BEGIN:VEVENT SUMMARY:Crystal structure of a silver-\, cobalt- and iron-based phosphate with an alluaudite-like structure: Ag 1.655 Co 1.64 Fe 1.36 (PO 4 ) 3 DTSTART;VALUE=DATE-TIME:20190131T111500Z DTEND;VALUE=DATE-TIME:20190131T113000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1615@events.saip.org.za DESCRIPTION:Speakers: Adam BOURAIMA (Mohammed V University\, Chemistry dep artment\, Rabat\, Morocco)\nThe new silver-\, cobalt- and iron-based phosp hate\, silver cobalt iron tris(orthophosphate)\,\nAg 1.655 Co 1.64 Fe 1.36 (PO 4 ) 3 \, was synthesized by solid-state reactions. Its structure is i sotypic to that\nof Na 2 Co 2 Fe(PO 4 ) 3 \, and belongs to the alluaudite family\, with a partial cationic disorder\, the\nAg I atoms being located on an inversion centre and twofold rotation axis sites (Wyckoff\nposition s 4a and 4e)\, with partial occupancies of 0.885 (2) and 0.7688 (19)\, res pectively. One\nof the two P atoms in the asymmetric unit completely fills one 4e site while the Co and Fe\natoms fill another 4e site\, with partia l occupancies of 0.86 (5) and 0.14 (5)\, respectively. The\nremaining Co 2 + and Fe 3+ cations are distributed on a general position\, 8f\, in a 0.39 (4):0.61 (4)\nratio. All O atoms and the other P atoms are in general pos itions. The structure is built up\nfrom zigzag chains of edge-sharing [MO6 ] (M = Fe/Co) octahedra stacked parallel to [101].\nThese chains are linke d together through PO 4 tetrahedra\, forming polyhedral sheets\nperpendicu lar to [010]. The resulting framework displays two types of channels runni ng along\n[001]\, in which the Ag I atoms (coordination number eight) are located as in show figure 1.\n\nhttps://events.saip.org.za/event/145/contr ibutions/1615/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1615/ END:VEVENT BEGIN:VEVENT SUMMARY:Pre Conference Workshop on Protein Crystallization DTSTART;VALUE=DATE-TIME:20190128T080000Z DTEND;VALUE=DATE-TIME:20190128T103000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1616@events.saip.org.za DESCRIPTION:Speakers: Tom Blundell (Cambridge University)\nhttps://events. saip.org.za/event/145/contributions/1616/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Amissah- Arthur Hall URL:https://events.saip.org.za/event/145/contributions/1616/ END:VEVENT BEGIN:VEVENT SUMMARY:Powder neutron diffraction and applications DTSTART;VALUE=DATE-TIME:20190128T153000Z DTEND;VALUE=DATE-TIME:20190128T170000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1617@events.saip.org.za DESCRIPTION:Speakers: Florence Porcher ()\nhttps://events.saip.org.za/even t/145/contributions/1617/ LOCATION:Bank of Ghana Conference Facility\, University of Ghana. URL:https://events.saip.org.za/event/145/contributions/1617/ END:VEVENT BEGIN:VEVENT SUMMARY:Introduction to hands on / Presentation of the Bruker D2 diffracto mer DTSTART;VALUE=DATE-TIME:20190128T173000Z DTEND;VALUE=DATE-TIME:20190128T190000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1618@events.saip.org.za DESCRIPTION:Speakers: Damien Cochet ()\nhttps://events.saip.org.za/event/1 45/contributions/1618/ LOCATION:Bank of Ghana Conference Facility\, University of Ghana. URL:https://events.saip.org.za/event/145/contributions/1618/ END:VEVENT BEGIN:VEVENT SUMMARY:CERN and AfLS Roadmap DTSTART;VALUE=DATE-TIME:20190201T144500Z DTEND;VALUE=DATE-TIME:20190201T150000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1620@events.saip.org.za DESCRIPTION:Speakers: Eckardt Elsen (CERN)\nhttps://events.saip.org.za/eve nt/145/contributions/1620/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1620/ END:VEVENT BEGIN:VEVENT SUMMARY:Influence of temporal pulse manipulation on quality of nonlinear i maging DTSTART;VALUE=DATE-TIME:20190129T163000Z DTEND;VALUE=DATE-TIME:20190129T163500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1626@events.saip.org.za DESCRIPTION:Speakers: George Okyere Dwapanyin (Stellenbosch University)\nT he in-depth study of the basic units of life requires the ability to probe deeper into cells and tissues in order to fully comprehend their function s. In recent years\, multiple linear optical imaging techniques (Confocal\ , STED\, Single Molecule Localized Microscopy etc.) have been developed in a number of different laboratories\, all aimed at probing deeper into bio logical tissue and enhancing image quality and resolution. Many of these advantages obtained with these advanced linear imaging modalities are inh erent in multiphoton imaging techniques (SHG\, two-photon fluorescence\, T HG\, CARS). These nonlinear optical microscopy (NLOM) techniques have the added advantage of intrinsic 3D imaging with submicron spatial resolution\ , decreased photodamage to tissue\, increased depth of penetration as well as the ability to perform label-free imaging. Where linear imaging techni ques focus on image enhancement through the manipulation of the spatial pr operties of the source\, NLOM techniques depend nonlinearly on the intensi ty. Hence\, we investigate the temporal shaping\, compression and modulati on of broad bandwidth laser pulses to manage the intensity of the pulses. In this presentation\, we look at how the manipulation of the temporal pro perties of the excitation source contributes to image enhancement. The pro cesses of supercontinuum generation from a highly nonlinear all normal dis persion fiber\, and temporal phase manipulation techniques together with s ome imaging results\, will be discussed.\n\nhttps://events.saip.org.za/eve nt/145/contributions/1626/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1626/ END:VEVENT BEGIN:VEVENT SUMMARY:Optical properties of PZN-4.5PT thin film deposited on silicon nan owires for photovoltaic application DTSTART;VALUE=DATE-TIME:20190129T174000Z DTEND;VALUE=DATE-TIME:20190129T174500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1627@events.saip.org.za DESCRIPTION:Speakers: Rémi NDIOUKANE (Laboratoire de Chimie et de Physiqu e des Matériaux (LCPM)\, Assane Seck University of Ziguinchor - Senengal) \nPerovskite solar cells have become a very hot research topic in photovol taics community. Since the initial reports on solid state perovskite solar cells with efficiency of 10 % in 2012 [1\,2]\, there has been a rapid inc rease in the number of publications in this area as well as rapid increase in the reported efficiencies. Certified record efficiency according to NR EL now exceeds 22 %. Despite this breakthrough\, hybrid lead-halide perovs kites are known to degrade due to moisture and heat\, upon prolonged expos ure to light and are prone to ion or halide vacancy migration\, leading to unstable operation of photovoltaic devices. To overcome such difficulties \, we oriented our research to inorganic PZN-PT perovskite materials with excellent and stable properties compared to the organic-perovskite ones. H owever\, despite their excellent properties\, one of the greatest difficul ties to integrate widely such materials in electronic devices is to achiev e them in thin films form because of their incongruent melting property.\n Our study focuses to integrate PZN-4.5PT as nanoparticles thin film on Sil icon substrate and to investigate their structural\, optical properties fo r photovoltaic application. PZN-4.5PT single crystals prepared using the c onventional high-temperature flux method were grounded in an agate mortar to obtain a very fine powder. This nanoparticles powder is then dispersed in a gel. After stirring for one hour in a magnetic mixer at low speed\, w e get a gelatinous solution containing PZN-4.5PT nanoparticles. A thin fil m is then deposit by spin coating on p-type silicon nanowires fabricated b y Ag assisted. After deposition\, SEM\, AFM and Micro Xray Fluorescence fo r thin film surface characterization were performed.\nKeywords: Perovskite \, nanoparticles\, thin layer\n\nhttps://events.saip.org.za/event/145/cont ributions/1627/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1627/ END:VEVENT BEGIN:VEVENT SUMMARY:Expression\, purification and preliminary crystallization of Schis tosomal universal stress G4LZI3 protein towards new schistosomide discover y DTSTART;VALUE=DATE-TIME:20190130T121500Z DTEND;VALUE=DATE-TIME:20190130T123000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1628@events.saip.org.za DESCRIPTION:Speakers: Abidemi Paul Kappo (Biotechnology and Structural Bio logy (BSB) Group\, University of Zululand\, KwaDlangezwa\, South Africa)\n The formation of high quality and perfect crystals forms the bottleneck an d rate-limiting step for structure determination by X-ray crystallography. Protein crystallography has formed an intricate part of the chemical\, bi otechnology and pharmaceutical industry as an important tool towards drug design\, protein engineering and in understanding various biological syste ms. In this study\, a Universal stress G4LZI3 protein\, identified as a ‘lead’ molecule for the design of alternative treatment against schist osomiasis\, was subjected to protein crystallization trials. Schistosoma m ansoni\, a parasitic helminth\, is responsible for the neglected tropical disease schistosomiasis that ranks second to malaria in public health sign ificance. It accounts for over 280 000 deaths per year and is equally to b lame for the physical life-long disability and disfigurements associated w ith the infection with an estimated global prevalence of 200 million. Praz iquantel\, which has been the gold standard for treatment for over 3 decad es\, has now exhibited drug resistance. Over-expression of the G4LZI3 prot ein throughout the schistosome’s lifecycle caused by conditions of stres s\, has warranted the need to determine its structure in a bid to design n ew schistosomides. \nThe gene sequence coding for the G4LZI3 protein was f irst cloned into a pQE-30 vector using BamH1 and HindIII restriction enzym es. The resultant pQE30-G4LZI3 construct was transformed into JM109 bacter ia cells. Expression screening was done to determine the best expressing c lone\, and was used for heterologous expression of sufficient amounts of r ecombinant G4LZI3 protein\, followed by purification on a Ni-NTA column. T hereafter\, the G4LZI3 protein was purified to homogeneity using size excl usion chromatography\; purified fractions under the chromatogram was poole d together and concentrated down to 10mg/ml\, 15mg/ml\, 17mg/ml\, 20mg/ml and 24mg/ml. These various concentrations were subjected to various crysta llization trials and various conditions yielded considerably sized and 3-d imensional shaped crystals. Future studies will aim to determine the struc ture and biological function of the protein\, as well as perform virtual s creening of identifying small molecule inhibitors that can serve as anti-s chistosomals.\nKeywords: Crystallization\, G4LZI3\, Praziquantel\, gel fil tration\, Schistosomiasis\n\nhttps://events.saip.org.za/event/145/contribu tions/1628/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1628/ END:VEVENT BEGIN:VEVENT SUMMARY:Suggested steps towards funding an Advanced Light Source Facility on the African Continent DTSTART;VALUE=DATE-TIME:20190130T150000Z DTEND;VALUE=DATE-TIME:20190130T153000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1629@events.saip.org.za DESCRIPTION:Speakers: Ernest malamud (Co-founders\, SciTech Science Cente r\, Illinois)\, Olivia Diaz (Co-founders\, SciTech Science Center\, Illin ois)\nIn this talk\, presented jointly\, we will briefly summarize our mul ti-faceted experience over several decades of building resources to fund a mbitious goals.\nSome of these goals were establishing a new regional hand s-on science center\,\nrunning an important political campaign and saving a treasured mountain lodge.\nWe will share the lessons learned of what wor ked and what didn’t work. The major part of our presentation will be a s uggested list of steps towards realizationof the dream of an AfLS and will conclude with a discussion among session participants.\n\nhttps://events. saip.org.za/event/145/contributions/1629/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1629/ END:VEVENT BEGIN:VEVENT SUMMARY:Synchrotron science applied to the Earth Sciences DTSTART;VALUE=DATE-TIME:20190129T120000Z DTEND;VALUE=DATE-TIME:20190129T121500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1635@events.saip.org.za DESCRIPTION:Speakers: Bjorn von der Heyden (Stellenbosch University)\nRece nt advancements in synchrotron technology have resulted in the advent of a n era in which ultra-high brilliance "Fourth Generation" synchrotron light sources promise to contribute significantly to high-level scientific rese arch. These X-rays provide tuneable\, high energy\, and high brilliance X- rays that can measure sub-ppm elemental concentrations on spatial scales a pproaching 10 nm. Despite these affordances\, synchrotron X-rays are relat ively under-utilised by researchers practicing in the broad field of the e arth sciences and notably in the field of ore geology research. \n\nThis p resentation serves to introduce the African geological and mineralogical c ommunities to the unique application of synchrotron light to e.g.\, coordi nation chemistry in fluids at geologically relevant P-T conditions\; fluid inclusion analyses\; distribution\, crystallographic siting and redox spe ciation of trace elements within ore mineral parageneses\; and characteris ation of poorly crystalline and sub-micrometer scale mineral precipitates. An overview of the different\, pertinent synchrotron X-ray analytical tec hniques will be provided and the technological specifications of commonly utilised synchrotron X-ray beam-lines will be explained. A number of case studies will be discussed focusing on the use of synchrotron X-rays to inv estigate important research questions related to mineralisation of preciou s metals (gold)\, base metals (zinc) and bulk commodities (Mn).\n\nFinally \, the presentation will highlight perceived future directions for the app lication of synchrotron light to ore-related research. The implications of this review will be discussed in a context of its relevance to African mi neralogical and geological research\, with special emphasis given to the p rospect of the African Light Source (AfLS\; a proposed/conceptualised sync hrotron facility on the African continent).\n\nhttps://events.saip.org.za/ event/145/contributions/1635/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1635/ END:VEVENT BEGIN:VEVENT SUMMARY:In Situ Characterization Tools for Quantum Materials DTSTART;VALUE=DATE-TIME:20190129T164500Z DTEND;VALUE=DATE-TIME:20190129T165000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1631@events.saip.org.za DESCRIPTION:Speakers: Prosper Ngabonziza (Max Planck Institute for Solid S tate Research)\nIn situ characterization of quantum materials\, in particu lar topological insulator nanomaterials using several\, and complementary surface analysis techniques enables to investigate topological surface sta tes without exposing the samples to ambient conditions. Adsorbants from ex posure to air and other ex situ contaminations result in notable changes i n the bulk and surface state properties of topological insulators. Here\, I will describe our recent developments in the in situ characterization of topological insulator nanomaterials.\nSpectroscopy techniques are some of the prominent synchrotron radiation based characterization tools\, in par ticular\, the X-ray photoemission spectroscopy (XPS) and angle resolved ph otoemission spectroscopy (ARPES). These techniques allow detailed study of the band structure and determination of elemental composition\, chemical state and physical properties of different materials. I will show one of o ur electronic structure measurements on strontium ruthenate materials perf ormed at Soleil synchrotron facility using ARPES. \nNext\, I will discuss our XPS and ARPES data on intrinsic Bi2Te3 topological insulator thin film s. Extensive studies on individual samples are made possible by connectin g the deposition chamber to a large number of surface analysis tools and b y using a vacuum suitcase technology that allows samples transfer in ultra -high vacuum conditions for further in-situ analysis at different location s like synchrotron radiation facilities.\n\nhttps://events.saip.org.za/eve nt/145/contributions/1631/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1631/ END:VEVENT BEGIN:VEVENT SUMMARY:Characterization of HVOF Inconel 625 Coating by X-ray diffraction and Synchrotron XRD DTSTART;VALUE=DATE-TIME:20190129T121500Z DTEND;VALUE=DATE-TIME:20190129T123000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1632@events.saip.org.za DESCRIPTION:Speakers: Philip Oluseyi Oladijo (Botswana International Unive rsity of Science and Technology)\nHigh-velocity oxy-fuel (HVOF) thermal sp raying is also a common deposition method used\, producing coatings of thi ckness ranging between 200 to 500 μm on engineering components. Despite t he attention received by HVOF over the years\, studies have shown that the re is less attention given to the development of thick coatings for repair applications\, most especially within the aerospace industry. Failure to produce thick coatings using HVOF methods is attributed to the residual st ress build-up encountered when coatings are deposited. The residual stress build-up associated with the production of thick coatings is unavoidable [1\, 2]\, and a major concern for the aerospace industry\, since the perfo rmance and lifespan of coatings is influenced by the presence of residual stresses. In this paper\, the investigation of depositing Inconel 625 of d ifferent coating thicknesses (250µm\, 300µm\, 400µm\, and 500µm) using high-velocity oxy-fuel (HVOF) technique on 304 stainless steel (SS) subst rate was conducted. The coating characterization was studied\, to determin e the best coating thickness to be applied on 304 SS substrates. The resid ual stresses of the as-sprayed coating were investigated using the Sin2ψ and Synchrotron X-ray diffraction (SR-XRD). The results indicate that the residual stressed have different nature despite using the same powder as f eedstock. In addition\, the magnitude of the residual stresses measured by X-rays was different from SR-XRD due to differences in their spatial reso lution and gauge volume.\n\nReference:\n1. A. M. Venter\, O.P. Oladijo\ , V. Luzin\, L.A. Cornish\, N. Sacks\, Thin Solid Films 549 (2013) 330- 33 9.\n2. O.P. Oladijo\, PhD Thesis\, University of the Witwatersrand Sout h Africa\, 2013.\n\nhttps://events.saip.org.za/event/145/contributions/163 2/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1632/ END:VEVENT BEGIN:VEVENT SUMMARY:IAEA support to utilization of large scale facilities by developin g countries. DTSTART;VALUE=DATE-TIME:20190130T103000Z DTEND;VALUE=DATE-TIME:20190130T110000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1634@events.saip.org.za DESCRIPTION:Speakers: Ian Swainson (IAEA)\nIAEA supports a variety of acti vities concerning large scale facilities. With respect to neutrons\, our a ctivities include technical meetings and coordinated research projects on topics such as neutron detection\, and modern cold moderators for research reactors and accelerator-based neutron sources. We also support via natio nal Technical Cooperation projects the development of neutron scattering i nstrumentation at research reactors.\n \nIAEA also supports access to\, an d training in\, synchrotron-based methods: we have sponsored projects in s upport of SESAME in Jordan since its inception\, providing training for st aff engineers and scientists and future users of synchrotron light\, suppl ying experts during design and commissioning of the ring\, and purchasing hardware\, such as radiation protection and monitoring equipment. We also run\, in partnership with Elettra\, the XRF beamline in Trieste\, Italy fo r which we provide some support for access to people from developing count ries. This beamline hosts an Ultra High Vacuum chamber\, whose core instru ment is a motorized 7-axis manipulator. This enables the use of different excitation/detection geometries\, integrating and implementing in one faci lity different X-ray spectrometry techniques with complementary analytical performance\, such as XRF and XANES in conventional\, grazing incidence o r exit incidence geometries as well as total reflection XRF and X-ray refl ectometry (XRR). At our laboratories in Seibersdorf\, Austria we have a du plicate of this: the “mirror chamber”. Training on its operation can take place offline in Austria before experiments are conducted at Elettra. Finally\, we provide travel support via cooperation agreements to a small number of meetings that cover topics in this area.\n\nhttps://events.saip .org.za/event/145/contributions/1634/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1634/ END:VEVENT BEGIN:VEVENT SUMMARY:Impact and solutions for electrical pollution and harmonics in Lin ac Accelerators used as injector in Synchrotrones DTSTART;VALUE=DATE-TIME:20190129T173500Z DTEND;VALUE=DATE-TIME:20190129T174000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1655@events.saip.org.za DESCRIPTION:Speakers: Mohamed Hedi TRABELSI (CNSTN)\nThis work will show s ome electrical pollution and problems (ineternal and external)\, met on tu nisian Facility \, equiped with a LINAC type of Electron beam accelerators (Power:5Kw\; Energy:10 MeV) used in many installation as an injector in s ynchrotrones\, and we will discuss some solutions for this electrical pro blems. \nWe will present some damages that can arised on systems of this t ype of facility\, due to electrical pollution.\nWith an accurate study\, r eal measurenments (analyzer three-phase networks) and computer simulations we will show the existence of significant levels of electrical harmonics\ , and finally we will discuss possible solutions : passive filtering or ac tive filtering.\n\nhttps://events.saip.org.za/event/145/contributions/1655 / LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1655/ END:VEVENT BEGIN:VEVENT SUMMARY:Induced defect levels of P and Al vacancy-complexes in 4H-SiC: A h ybrid functional study DTSTART;VALUE=DATE-TIME:20190129T171500Z DTEND;VALUE=DATE-TIME:20190129T172000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1637@events.saip.org.za DESCRIPTION:Speakers: Emmanuel Igumbor (University of Pretoria)\nThe elect ronic behaviour of high-dose phosphorus implanted in 4H-SiC is mainly desi rable to obtained lower sheet resistance of 4H-SiC. Al doping on the other hand acts as an acceptor\, improves the dielectric properties of 4H-SiC a nd has very low diffusivity in SiC. Using a hybrid density functional theo ry\, we investigated the properties of Al and P defect-complexes in 4H-SiC a wide band-gap semiconductor that is promising for applications in high- frequency and high-temperature electronic device. We show that vacancy-com plexes formed by PSi and AlSi are more energetically stable than those for med by PC and AlC. The defects with silicon vacancy are predicted to exper ience more lattice distortion compared to those formed with carbon vacancy . While vacancy-complexes formed with PSi or PC and VC induced double dono r levels\, vacancy-complex formed with substitution of P and VSi induced n egative-U charge state ordering. The Al with VC related vacancy-complexes induced deep single donor and acceptor levels\, and Al with VSi induced on ly acceptor and negative-U ordering.\n\nhttps://events.saip.org.za/event/1 45/contributions/1637/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1637/ END:VEVENT BEGIN:VEVENT SUMMARY:PZN-4.5PT single crystals and nanoparticles thin Films Characteriz ation using XRD and Synchrotron Light Sources DTSTART;VALUE=DATE-TIME:20190129T114500Z DTEND;VALUE=DATE-TIME:20190129T120000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1638@events.saip.org.za DESCRIPTION:Speakers: Diouma Kobor (University Assane Seck of Ziguinchor)\ nPZN-PT single crystals showed properties up to 10 times more interesting than\nthose of the ferroelectric perovskite materials currently used. Howe ver\, the\ngreatest difficulty to use PZN-4.5PT single crystals on electro nic devices is to\nachieve them in thin layers form because of their incon gruent melting property.\nIn this work we fabricate with success thin film s by dispersing these\nnanoparticles in a gel. The as fabricated thin film s showed colossal dielectric\npermittivity large than 105. However\, we fo und from SEM images the formation\nof non-identified hexagonal microcrysta ls\, which could be the origin of such\nexcellent properties. These requir e intensive investigations to identify such\nhexagonal components and the phase changes in dielectric-temperature\ncharacteristic.\nSynchrotron ligh t source was used to characterize the influence of manganese\ndoping on th e single crystals using XANES spectroscopy at ESRF. Philips X’Pert\nPro XRD diffractometer was used to identify the hexagonal microcrystals and th e\nphase changes using temperature chamber coupled to the diffractometer.\ n\nhttps://events.saip.org.za/event/145/contributions/1638/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1638/ END:VEVENT BEGIN:VEVENT SUMMARY:Diffraction Physics DTSTART;VALUE=DATE-TIME:20190128T090000Z DTEND;VALUE=DATE-TIME:20190128T103000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1639@events.saip.org.za DESCRIPTION:Speakers: Giblerto Artioli (Università di Padova\, Dipartimen to di Geoscienze\, Padova\, Italy)\nhttps://events.saip.org.za/event/145/c ontributions/1639/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1639/ END:VEVENT BEGIN:VEVENT SUMMARY:Introduction to powder diffraction geometry and instrumentation DTSTART;VALUE=DATE-TIME:20190128T110000Z DTEND;VALUE=DATE-TIME:20190128T130000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1640@events.saip.org.za DESCRIPTION:Speakers: Gilberto Artioli (Università di Padova\, Dipartimen to di Geoscienze\, Padova\, Italy)\nhttps://events.saip.org.za/event/145/c ontributions/1640/ LOCATION:Bank of Ghana Conference Facility\, University of Ghana. URL:https://events.saip.org.za/event/145/contributions/1640/ END:VEVENT BEGIN:VEVENT SUMMARY:Multi analyses on inorganic materials DTSTART;VALUE=DATE-TIME:20190131T103000Z DTEND;VALUE=DATE-TIME:20190131T110000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1641@events.saip.org.za DESCRIPTION:Speakers: Michele Zema (International Union of Crystallography )\nMulti analyses on inorganic materials\n\nhttps://events.saip.org.za/eve nt/145/contributions/1641/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1641/ END:VEVENT BEGIN:VEVENT SUMMARY:Clays and bricks DTSTART;VALUE=DATE-TIME:20190131T121500Z DTEND;VALUE=DATE-TIME:20190131T123000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1642@events.saip.org.za DESCRIPTION:Speakers: Lébé Prisca (Felix Houphouët-Boigny University\, Ivory Coast)\nClays and bricks\n\nhttps://events.saip.org.za/event/145/con tributions/1642/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1642/ END:VEVENT BEGIN:VEVENT SUMMARY:Hard X-ray Spectroscopy and Imaging at the BAMline and µSpot beam lines @BESSY II (Berlin\, Germany) DTSTART;VALUE=DATE-TIME:20190130T154500Z DTEND;VALUE=DATE-TIME:20190130T160000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1643@events.saip.org.za DESCRIPTION:Speakers: Ana Buzanich Guilherme (Bundesanstalt für Material forschung und -prüfung (BAM)\nThe BAMline and the µSpot beamlines are ha rd X-ray multipurpose stations. The common X-ray source is a 7 Tesla wavel ength shifter (WLS) installed at the Berlin Electron Storage Ring for Sync hrotron Radiation (BESSY II). Such source enables a continuous broad energ etic spectrum up to 100 keV\, which is optimal for implementing various an alytical methods. The BAMline was the first hard X-ray beamline being inst alled at BESSY II in 2001 [1] followed by the µSpot beamline in 2004 [2]. \nBoth beamlines are versatile but somewhat different regarding their opt ical elements. The main difference is the existence of a toroidal mirror a t the µSpot beamline placed at 13 m after the source. The beam is sagitta l focused down to a 300 µm diameter 20 m thereafter. The mirror allows pe rforming several experiments at the micrometer scale but\, due to its refl ectivity\, in the energy range between 2-25 keV ‘only’. A total flux o f 1013 photons/s/100mA @ 8 keV is achieved [2]. The µSpot beamline posses ses three different monochromators with distinct energy resolutions: B4C/M o (2x10-3)\, Si 111(2x10-4) and Si 311 (4x10-5). The BAMline has the possi bility to experiment at energies between 4 to 100 keV but with one order o f magnitude lower in photon flux. The optical elements are two monochromat ors with different energy resolutions\, depending on the desired experimen t: W/Si (1.6x10-2) and Si 111 (2x10-4).\nAt the BAMline the available anal ytical methods fall into the three main groups: X-ray fluorescence spectro scopy (XRF)\, X-ray absorption spectroscopy (XAS) and X-ray computed tomog raphy (CT). At the µSpot the same spectroscopic methods are available wit h the possibility of performing microanalysis\, as the name suggests. Besi des spectroscopy\, diffraction techniques are also available at the µSpot beamline: X-ray diffraction (XRD) and X-ray scattering in both small-angl e (SAXS) and wide-angle (WAXS) configurations. Presently\, several variati ons of these methods are accessible to the (scientific) community. The aim is to optimize the fields of application of materials by means of differe nt analytical methods. Actual pertinent fields of investigation are cataly sis\, ‘green chemistry’\, material\, biology\, medicine and environmen t. Several examples will be presented.\n\nhttps://events.saip.org.za/event /145/contributions/1643/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1643/ END:VEVENT BEGIN:VEVENT SUMMARY:Pan African thinking and strategy DTSTART;VALUE=DATE-TIME:20190201T152000Z DTEND;VALUE=DATE-TIME:20190201T153500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1644@events.saip.org.za DESCRIPTION:Speakers: Nkem Khumbah (Next Einstein Forum (NEF) and Universi ty of Michigan)\nTBA\n\nhttps://events.saip.org.za/event/145/contributions /1644/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1644/ END:VEVENT BEGIN:VEVENT SUMMARY:The Lyncean Compact Light Source\, A Stepping Stone of the Path To wards an African Light Source? DTSTART;VALUE=DATE-TIME:20190128T163000Z DTEND;VALUE=DATE-TIME:20190128T170000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1645@events.saip.org.za DESCRIPTION:Speakers: Jackie Kasahara (Lyncean Technologies\, Inc.)\nWe wi ll discuss the contribution of synchrotron radiation facilities to a regio n's research infrastructure and the challenges in building such a facility \, in particular for regions with limited expertise and budget. We will d escribe how the Lyncean Compact Light Source (CLS) generates synchrotron-l ike X-ray beams with a much smaller footprint\, how the performance compar es to both conventional laboratory and synchrotron X-ray sources\, and wha t applications are enabled by the CLS's unique beam properties. Finally\, we will explore how the CLS can be a stepping stone towards building a la rge synchrotron facility by providing valuable expertise in the operation and maintenance of a storage ring\, the opportunity to build a local\, mul ti-disciplinary user community\, as well as expertise in beamline developm ent and X-ray applications.\n\nhttps://events.saip.org.za/event/145/contri butions/1645/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1645/ END:VEVENT BEGIN:VEVENT SUMMARY:The Lyncean Compact Light Source\, A Multi-Discipline Source for t he Modern X-ray Facility DTSTART;VALUE=DATE-TIME:20190129T174500Z DTEND;VALUE=DATE-TIME:20190129T175000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1646@events.saip.org.za DESCRIPTION:Speakers: Jack Kasahara (Lyncean Technologies\, Inc.)\nThe Lyn cean Compact Light Source (CLS) is a “table-top” synchrotron that prov ides many of the beam qualities found at a large government operated synch rotron\, such as high flux\, quasi-monochromatic and continuously energy t unable. These beam qualities enable a variety of synchrotron quality meas urements to be performed such as imaging/CT\, diffraction\, scattering and spectroscopy\, making the CLS an ideal cornerstone for a university or re search institute based\, multi-disciplined X-ray facility. The technology behind the CLS will be discussed\, as well as applications being performe d at the Biomedical Engineering Dept. of the Technical University of Munic h.\n\nhttps://events.saip.org.za/event/145/contributions/1646/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1646/ END:VEVENT BEGIN:VEVENT SUMMARY:Irradiation effects of swift heavy ions on palladium films deposit ed on 6H-SiC substrate DTSTART;VALUE=DATE-TIME:20190130T111500Z DTEND;VALUE=DATE-TIME:20190130T113000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1647@events.saip.org.za DESCRIPTION:Speakers: Thabsile Thabethe (University of Pretoria)\nThe irra diation effect of swift heavy ions on palladium (Pd) films deposited on 6H -SiC was investigated. The samples were irradiated by Xe26+ ions with the energy of 167 MeV at fluences of 1 × 1013 cm-2 and 3 × 1014 cm-2 at roo m temperature. Phase identification\, residual stress and surface morpholo gy were investigated with X-ray diffraction (XRD)\, synchrotron diffractio n and scanning electron microscopy (SEM). The results showed that the as-d eposited sample was composed of Pd and SiC with no evidence of a reaction between Pd and SiC. No reaction was observed for the lower irradiation flu ence\, only an increase in the Pd peak intensities was observed indicating improvement in the crystallinity of the material. A reaction between Pd and SiC forming PdSi and Pd2Si was observed after irradiation at a fluence of 3 × 1014 cm-2. The stress measurements indicated that the films were having tensile and biaxial stress not exceeding 200 MPa. A decrease in st ress values was observed with an increase in irradiation fluence. The surf ace morphology of the as-deposited was flat and composed of small granules . There was an increase in granule sizes due to irradiation at 1×1013 cm- 2. Irradiating at 3×1014 cm-2 caused grain agglomeration and clustering.\ n\nhttps://events.saip.org.za/event/145/contributions/1647/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1647/ END:VEVENT BEGIN:VEVENT SUMMARY:Welcome Address DTSTART;VALUE=DATE-TIME:20190128T084500Z DTEND;VALUE=DATE-TIME:20190128T090000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1648@events.saip.org.za DESCRIPTION:Speakers: Claude Lecomte ()\nhttps://events.saip.org.za/event/ 145/contributions/1648/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1648/ END:VEVENT BEGIN:VEVENT SUMMARY:START - Synchrotron Techniques for African Science and Technology DTSTART;VALUE=DATE-TIME:20190130T110000Z DTEND;VALUE=DATE-TIME:20190130T111500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1649@events.saip.org.za DESCRIPTION:Speakers: Mkwizu Tumaini (University of the Witwatersrand)\nST ART - Synchrotron Techniques for African Science and Technology\, is Resea rch Councils United Kingdom (RCUK) funded research consortium under its Gl obal Change Research Fund (GCRF) programme\, primarily to facilitate acces s and collaboration around the use of Synchrotron Techniques. Towards this end\, the consortium is organised two distinct thematic lines\, that addr ess their respective needs and modalities of accessing synchrotron based t echniques. The first theme focussing on Energy materials whilst the second focusses on Structural biology\n\nOverall the consortium formally compris es 17 institutions from 5 countries. \n\nBackground information around th e formation of START will be presented as well as brief summaries of some of the current and proposed research by the members of the consortium.\n\n https://events.saip.org.za/event/145/contributions/1649/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1649/ END:VEVENT BEGIN:VEVENT SUMMARY:Lightsources for Africa\, the Americas\, Asia and Middle East Proj ect (LAAAMP): An IUPAP and IUCr ICSU-Funded Project DTSTART;VALUE=DATE-TIME:20190130T165000Z DTEND;VALUE=DATE-TIME:20190130T171000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1650@events.saip.org.za DESCRIPTION:Speakers: Sekazi Mtingwa (TriSEED Consultants\, LLC (USA))\nWe describe a new initiative funded by a 3-year\, 300K-Euro grant from the I nternational Council for Science (ICSU) to the International Union of Pure and Applied Physics (IUPAP) and International Union of Crystallography (I UCr) in collaboration with over thirty partner organizations that include sixteen advanced light sources to enhance the utilization of advanced ligh t sources and crystallography in five targeted regions of the world\, name ly Africa\, the Caribbean\, Mexico\, Southeast Asia\, and Middle East. LA AAMP’s programs include the development of a Strategic Plan for each reg ion\; a Colloquium program that sends experienced light source and crystal lography users to those regions\; establishment of new IUCr-UNESCO Crystal lography OpenLabs\; design and distribution of a Brochure that describes a dvanced light sources and crystallography for government officials and the public\; 2-month Faculty-Student (FAST) Team training visits to advanced light sources\, with approximately forty new users participating in 2017-2 018\; and culminating in a December 2019 meeting to chart a path forward b eyond the ICSU grant.\n\nhttps://events.saip.org.za/event/145/contribution s/1650/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1650/ END:VEVENT BEGIN:VEVENT SUMMARY:Synthesis\, Characterization and Environmental Application of Ag-A g 3 PO 4 Photocatalyst DTSTART;VALUE=DATE-TIME:20190129T163000Z DTEND;VALUE=DATE-TIME:20190129T164500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1651@events.saip.org.za DESCRIPTION:Speakers: Emmanuel Nyankson (Department of Materials Science a nd Metallurgy\, University of Cambridge\, UK)\nThe accidental release of c rude oil and water-soluble dyes into our marine environment is a\nmajor co ncern of the environmental protection agency of most countries worldwide. Different\nmaterials are therefore being developed and investigated for th eir potential application in\nremediating these pollutants. Semiconductor based photocatalysts have been examined for their\npotential in solving ma ny environmental and energy problems. Developing highly efficient\nvisible light active photocatalyst which can be used in environmental remediation has therefore\nbecome the focus of most researchers. A highly efficient A g-Ag 3 PO 4 photocatalyst was\nsynthesized by a modified precipitation met hod. The as-synthesized Ag-Ag 3 PO 4 was\ncharacterized with X-ray diffrac tion (XRD)\, scanning electron microscopy (SEM)\, energy\ndispersive spect roscopy (EDS)\, Raman spectroscopy\, and X-ray photoelectron spectroscopy\ n(XPS). The Ag-Ag 3 PO 4 photocatalyst showed an increase of over 300 % in rate of photocatalytic\ndegradation of rhodamine blue dye when compared t o Ag 3 PO 4 under visible light illumination.\nHeat treatment of the as sy nthesized Ag-Ag 3 PO 4 almost doubled its pseudo first order rate\nconstan t for the degradation of rhodamine blue dye. The synthesized photocatalyst was stable\nafter cycles of photocatalytic degradation of rhodamine blue dye. The potential application of the\nAg-Ag 3 PO 4 in oil spill remediati on was examined through photocatalytic degradation of\nasphaltene\, aromat ic and paraffin components in crude oil. UV-vis\, FTIR and GC-MS analysis of\nthe oil components after visible light irradiation showed excellent de gradation with the formation\nof intermediate photoproducts. The photocata lytic activity enhancement of the Ag-Ag 3 PO 4 can be\nattributed to the g ood electron trapping role of Ag nanoparticles deposited on the surface of the\nAg 3 PO 4 . Th results from the study showed the potential applicati on of Ag-Ag 3 PO 4 photocatalyst\nin environmental remediation.\n\nhttps:/ /events.saip.org.za/event/145/contributions/1651/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1651/ END:VEVENT BEGIN:VEVENT SUMMARY:Palaeontology: Highlights of X-ray computed tomography at the syn chrotrons DTSTART;VALUE=DATE-TIME:20190129T140000Z DTEND;VALUE=DATE-TIME:20190129T143000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1652@events.saip.org.za DESCRIPTION:Speakers: Kudakwashe Jakata (University of the Witwatersrand)\ nFossils remains of animals that existed in periods such as the Permian\, Triassic and Jurassic eras have been discovered in Africa. There is also a n extensive collection of human ancestral remains from a few million years ago or less that have been found such as Australopithecus Sediba\, Turkan a Boy (Homo ergaster)\, Zinjathropus (Parantropus boisei) and Sahelanthrop us tchadensis which have added to our understanding of the history of life on earth. The discovery of the earliest hominid remains on our continent has led to the designation of Africa as “the cradle of mankind”. X-ra y computed tomography (CT) provides a useful way of studying fossil materi als which are rare and sometimes fragile. It allows researchers to observe the internal structures and take measurements that can be used to make us eful comparisons and answer questions on subjects such as locomotion and p ossible diets. There are now many laboratory based CT scanners available from which resolutions in the micrometre and nanometre ranges can be obtai ned depending on the size of the specimen. However\, laboratory based scan ners have limitations on the X-ray flux and energy which can be generated. This has led to the use of synchrotron facilities to study some of the fo ssil remains. We present the highlights of CT scanning of African fossils at synchrotron facilities and the future of 3D computed tomography. \nWe a lso present an investigation into the nature of some of the high density i nclusions which are occasionally observed after a scan of a fossil which c an result in a loss of contrast. We have determined the nature of the high density materials as iron and manganese in one such sample using X-ray fl uorescence (XRF). Complimentary techniques such as X-ray diffraction (XRD) and Mössbauer spectroscopy have also been used to further characterize t hese inclusions. This information may be useful when some of the specimens have to be taken to a synchrotron for scanning as is sometimes the case.\ n\nhttps://events.saip.org.za/event/145/contributions/1652/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1652/ END:VEVENT BEGIN:VEVENT SUMMARY:Magnetic properties of the layered structure Pr3Os4Al12 compound DTSTART;VALUE=DATE-TIME:20190129T165000Z DTEND;VALUE=DATE-TIME:20190129T170000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1653@events.saip.org.za DESCRIPTION:Speakers: Michael Ogunbunmi (University of Johannesburg)\nWe h ave investigated the physical and magnetic properties of the hexagonal Kag ome lattice structure compound Pr3Os4Al12 which crystallizes in the hexago nal Gd3Ru4Al12-type structure with space group P63/mmc (No. 194). The comp ound shows a long-range magnetic ordering of the Pr3+ moment at TC = 37 K as indicated by the temperature dependences of magnetic susceptibility\, s pecificc heat and electrical resistivity. The magnetic ordering is associa ted with the frustration of the magnetic spins which are located on a tria ngular Kagome lattice. The electrical resistivity shows a spin-gap behavio r below TC.\n\nhttps://events.saip.org.za/event/145/contributions/1653/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1653/ END:VEVENT BEGIN:VEVENT SUMMARY:OPEN SESAME: European support to the SESAME Light Source in the Mi ddle East DTSTART;VALUE=DATE-TIME:20190130T143000Z DTEND;VALUE=DATE-TIME:20190130T150000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1656@events.saip.org.za DESCRIPTION:Speakers: Edward Mitchell (ESRF)\nThe OPEN SESAME (www.openses ame-h2020.eu) project is supporting optimal exploitation of the Synchrotro n light for Experimental Science and Applications in the Middle East (SESA ME) light source. With this aim\, OPEN SESAME has three key objectives: \n 1. To train SESAME staff in the storage ring and beamline instrumentation technology\, research techniques and administration for optimal use of a m odern light source facility.\n2. To build-up human capacity in Middle East researchers to optimally exploit SESAME’s infrastructure.\n3. To train SESAME staff and its user community in public outreach and corporate commu nications\, and to support SESAME and its stakeholders in building awarene ss and demonstrating its socio-economic impact to assure longer term explo itation. \n \nEach objective is tackled by a work package. Firstly\, S ESAME staff training is addressed by 65 staff exchanges planned between SE SAME and the European partners. Secondly\, capacity-building is targeted b y five training schools\, a short-term fellowship programme and an industr ial workshop. Finally\, a proactive communications strategy will be create d\, including an educational “roadshow” to all of the SESAME Members\, and a training programme in research infrastructure administration and th eir economic role and impact for young science managers of SESAME Member s takeholders. \n\nOPEN SESAME expects to have a lasting impact on a reinfor ced European Research Area\, and particularly in strengthening internation al cooperation for research infrastructures with a key Region located clos e to Europe.\n\nThe OPEN SESAME consortium is composed of ten European ins titutes (six light sources\, The Cyprus Institute\, CERN\, CNRS and Instru ct) along with SESAME itself.\n\nThe OPEN SESAME project has received fund ing from the EU's H2020 Framework Programme for research and innovation un der grant agreement n.730943.\n\nhttps://events.saip.org.za/event/145/cont ributions/1656/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1656/ END:VEVENT BEGIN:VEVENT SUMMARY:Cooperative Brilliance DTSTART;VALUE=DATE-TIME:20190128T113000Z DTEND;VALUE=DATE-TIME:20190128T120000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1657@events.saip.org.za DESCRIPTION:Speakers: Andrea Lausi (Elettra Sincrotrone Trieste)\nElettra is one of the first 3rd generation storage rings\, successfully upgraded t o routinely operate in top-up mode at both 2.0 and 2.4 GeV. The former Lin ear Accelerator injector has been completely rebuilt as a new FEL source\, FERMI\, developed to provide fully coherent ultrashort (10-100 femtosecon d) pulses with a peak brightness ten billion times higher than that made a vailable by third-generation light sources in the ultraviolet and soft x-r ay range.\nElettra hosts four dedicated beamlines for crystallography\, tw o open to the users and two under construction\, and expected to be ready for public use in 2015. In service since 1994\, XRD1 is a general purpose diffraction beamline. The light source for this wide (4-21 keV) energy ran ge beamline is a permanent magnet wiggler. XRD1 covers experiments ranging from grazing incidence X-ray diffraction to macromolecular crystallograph y\, from industrial applications of powder diffraction to X-ray phasing wi th long wavelengths. The bending magnet powder diffraction beamline MCX ha s been open to users since 2009\, with a focus on microstructural investig ations and studies under non-ambient conditions. A superconducting wiggler delivers a high photon flux to a new fully automated beamline dedicated t o macromolecular crystallography and to a branch beamline hosting a high p ressure powder X-ray diffraction station (both currently under constructio n). A high throughput crystallization platform equipped with an imaging sy stem for the remote viewing\, evaluation and scoring of the macromolecular crystallization experiments\, has also been established and is open to th e user community.\nSynchrotron radiation science owes its success to its i mpact in the science of materials considered in the widest sense\, where h igh quality performance experiments require high quality beamline instrume ntation. The challenges for beamline engineering\, from managing high heat loads to the development high stability optics\, to are common to all of the light sources. Therefore\, the development of a new beamline necessari ly implies the set-up of collaborative structures that involve a broad exp anse over the synchrotron radiation community. As a matter of fact\, all b eamlines include common elements such as X-ray optics\, experimental stati ons\, detectors and beamline control so that the collaborative development of common technology platforms has proven crucial in enabling the communi ty to handle sophisticated instrumentation whilst still allowing customiza tion to particular user and experiment demands.\n\nhttps://events.saip.org .za/event/145/contributions/1657/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryetey Hall URL:https://events.saip.org.za/event/145/contributions/1657/ END:VEVENT BEGIN:VEVENT SUMMARY:Nanostructured Cuprous Oxide Powder via High Energy Milling DTSTART;VALUE=DATE-TIME:20190129T113000Z DTEND;VALUE=DATE-TIME:20190129T114500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1658@events.saip.org.za DESCRIPTION:Speakers: Dodoo-Arhin David (University of Ghana)\nThe Whole P owder Pattern Modelling technique was employed to investigate the microstr ucture changes in Cuprous Oxide powders milled in a vibrating cup mill. Th e effect of milling on the microstructure evolution was investigated using Synchrotron Radiation XRD and standard XRD line profile analysis supporte d with HRTEM and ESEM techniques. The reduction in the average size of coh erently scattering domains - and simultaneous narrowing of the size distri bution – occurs in the first minutes. An asymptotic limit of ca. 10 nm i s obtained. The reduction in size is obtained at the expenses of introduci ng a massive quantity of dislocations in the system\, reaching a limit of ca. 4×10-16 m-2. A proper nanocrystalline microstructure can be obtained with an effective milling time of ca. 20 min.\n\nhttps://events.saip.org.z a/event/145/contributions/1658/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1658/ END:VEVENT BEGIN:VEVENT SUMMARY:Laser Sources and their Applications - An Overview DTSTART;VALUE=DATE-TIME:20190130T113000Z DTEND;VALUE=DATE-TIME:20190130T114500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1659@events.saip.org.za DESCRIPTION:Speakers: Paul Kingsley Buah-Bassuah (Laser and Fibre Optics C entre (LAFOC) Department of Physics University of Cape Coast\, Ghana)\nLas er sources have undergone a lot of innovation covering almost all the elec tromagnetic\nspectrum. The use of lasers in Agriculture\, industry\, medic ine\, material science\, molecular\nbiology\, holography and energy turns to put a better price on investing into such technology.\nThis paper attem pts to introduce photonics as a main tool in Laser applications and the\nf abrication of free electron laser radiation from Synchrotron source. An ov erview and\npotential use of lasers in solving problems in developing coun tries will be appraised.\n\nhttps://events.saip.org.za/event/145/contribut ions/1659/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1659/ END:VEVENT BEGIN:VEVENT SUMMARY:How Crystallography can Influence the Sustainability of Cement-bas ed products DTSTART;VALUE=DATE-TIME:20190129T174500Z DTEND;VALUE=DATE-TIME:20190129T180000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1660@events.saip.org.za DESCRIPTION:Speakers: M Bediako (Unknown)\nHow Crystallography can Influen ce the Sustainability of Cement-based products\n\nhttps://events.saip.org. za/event/145/contributions/1660/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1660/ END:VEVENT BEGIN:VEVENT SUMMARY:Synthesis\, characterization and thermoelectric properties of poly mer blend Bi22.5Sb7.5Te70 composite DTSTART;VALUE=DATE-TIME:20190129T173000Z DTEND;VALUE=DATE-TIME:20190129T174500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1661@events.saip.org.za DESCRIPTION:Speakers: N Demoze (Unkown)\nSynthesis\, characterization and thermoelectric properties of polymer blend Bi22.5Sb7.5Te70 composite\n\nht tps://events.saip.org.za/event/145/contributions/1661/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1661/ END:VEVENT BEGIN:VEVENT SUMMARY:Crystal\, electronic structure\, optical and electrical studies of new 2D hybrid perovskite promising for photovoltaic applications DTSTART;VALUE=DATE-TIME:20190129T164500Z DTEND;VALUE=DATE-TIME:20190129T170000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1662@events.saip.org.za DESCRIPTION:Speakers: K. Abdel-Aal Seham (Cairo University)\nCrystal\, ele ctronic structure\, optical and electrical studies of new 2D hybrid perovs kite promising for photovoltaic applications\n\nhttps://events.saip.org.za /event/145/contributions/1662/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1662/ END:VEVENT BEGIN:VEVENT SUMMARY:Excillum DTSTART;VALUE=DATE-TIME:20190131T124500Z DTEND;VALUE=DATE-TIME:20190131T130000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1663@events.saip.org.za DESCRIPTION:Speakers: Emil Espes ()\nhttps://events.saip.org.za/event/145/ contributions/1663/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Bank of Ghana Auditorium URL:https://events.saip.org.za/event/145/contributions/1663/ END:VEVENT BEGIN:VEVENT SUMMARY:Cocrystals and Metal Complexes: Synthesis\, Structural Elucidation and Applications DTSTART;VALUE=DATE-TIME:20190129T171500Z DTEND;VALUE=DATE-TIME:20190129T173000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1664@events.saip.org.za DESCRIPTION:Speakers: Olufunso Abosede (Federal University Otuoke\, Nigeri a)\nCocrystals and Metal Complexes: Synthesis\, Structural Elucidation and Applications\n\nhttps://events.saip.org.za/event/145/contributions/1664/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1664/ END:VEVENT BEGIN:VEVENT SUMMARY:Separation of Trimethoxybenzene Isomers by Bile Acids DTSTART;VALUE=DATE-TIME:20190130T172000Z DTEND;VALUE=DATE-TIME:20190130T174000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1674@events.saip.org.za DESCRIPTION:Speakers: Jacky S Boudiombo (Department of Chemistry\, Univers ity of Cape Town\, Private Bag\, Rondebosch 7701\, South Africa)\nMolecula r selectivity by host-guest procedures is an increasing method to help in the separation of\nenantiomers. In this study\, two similar bile acids\, c holic acid (CA) and deoxycholic acid (DCA)\, were\nused as hosts to separa te the mixtures of several isomer guests. The different compounds prepared \nwere analyzed by single crystal X-Ray diffraction. Our first guest mixtu res were the isomers of\ntrimethoxybenzene (TMB) whose normal boiling poin ts range from 241 to 255℃. We prepared\nequimolar mixtures of the three isomers in pairs and dissolved the CA/DCA host in them\, such that\nthe to tal guest to host ratio was 5. The selectivity preference is CA: TMB135 > TMB123 ≈ TMB124\,\nwhile it is reversed for DCA: TMB123 > TMB124 > TMB13 5. Some of the crystal structures with\nCA as host suffered from partial d isorder\, while the DCA structures were grown from pairs of\nequimolar gue st mixtures\, and all contained both guests in different proportions. Pack ing analysis\nrevealed the importance of layering of the hydrophilic and l ipophilic regions of the structures with the\nTMB guests accommodated in t he lipophilic layers. Further analytical measurements carried out by\nNMR are in agreement with the structural results.\n\nhttps://events.saip.org.z a/event/145/contributions/1674/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1674/ END:VEVENT BEGIN:VEVENT SUMMARY:Introduction to Pair Distribution Function Analysis (PDF) DTSTART;VALUE=DATE-TIME:20190128T140000Z DTEND;VALUE=DATE-TIME:20190128T153000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1675@events.saip.org.za DESCRIPTION:Speakers: El-Eulmi Bendeif ()\nhttps://events.saip.org.za/even t/145/contributions/1675/ LOCATION:Bank of Ghana Conference Facility\, University of Ghana. URL:https://events.saip.org.za/event/145/contributions/1675/ END:VEVENT BEGIN:VEVENT SUMMARY:Goethite functionalised cyclodextrin nanosponge for the removal of organic\, inorganic and microbial contaminants from drinking water DTSTART;VALUE=DATE-TIME:20190129T170000Z DTEND;VALUE=DATE-TIME:20190129T171500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1665@events.saip.org.za DESCRIPTION:Speakers: Nangah Che Randy (University of Yaounde\, Cameroon)\ nMore people die globally from consuming polluted water than are killed by all forms of violence including wars [1\,2]. In Cameroon\, water crisis h as driven the population to consuming water from sources that have a high- risk potential for infection [3]\, resulting to the insurgence of cholera outbreaks (657 deaths) [4]\, and increased occurrence of typhoid and diarr hoea. This paper delineates the synthesis and characterisation of goethite functionalised cyclodextrin nanosponge through ultrasound-assisted polyco ndensation polymerisation and its application for removal of different cla sses of pollutants. The as-prepared nanosponges were characterised by x-ra y diffraction\, transmission electron microscopy\, scanning electron micro scopy\, Fourier transform infrared\, and thermogravimetric analysis. From the adsorption tests\, we observe a 99.98 % methylene blue (MB) adsorption using 0.1 g of adsorbent and 20 ppm of MB solution. At a nickel(II) and f luoride ion concentration of 50 ppm\, a maximum equilibrium adsorption of 97.28 % and 71.33 % was recorded respectively after 10 mins. Studies on E Coli removal showed a removal of 83.75 %. Column adsorption for MB and nic kel (II) was carried out using 20 ppm of MB solution\, 50 ppm nickel (II)\ , 1 g of adsorbent at a flow rate of 5 ml/min. After five hours for both c ases\, the removal of these species was still in the 99.93 -99.96 % range. This result demonstrated the affinity of the as- prepared nanosponges to bind and remove effectively different classes of pollutants from water and its potential for point-of-use water purification systems.\n\nhttps://eve nts.saip.org.za/event/145/contributions/1665/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1665/ END:VEVENT BEGIN:VEVENT SUMMARY:African Light Source Project DTSTART;VALUE=DATE-TIME:20190129T092000Z DTEND;VALUE=DATE-TIME:20190129T093000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1666@events.saip.org.za DESCRIPTION:Speakers: Simon Connell (University of Johannesburg)\nhttps:// events.saip.org.za/event/145/contributions/1666/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1666/ END:VEVENT BEGIN:VEVENT SUMMARY:IUCr Africa Initiative DTSTART;VALUE=DATE-TIME:20190129T091000Z DTEND;VALUE=DATE-TIME:20190129T092000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1667@events.saip.org.za DESCRIPTION:Speakers: Claude Lecomte ()\nhttps://events.saip.org.za/event/ 145/contributions/1667/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1667/ END:VEVENT BEGIN:VEVENT SUMMARY:International Science Council – Regional office of Africa. Overv iew DTSTART;VALUE=DATE-TIME:20190131T123000Z DTEND;VALUE=DATE-TIME:20190131T124500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1668@events.saip.org.za DESCRIPTION:Speakers: Daniel Nyanganyura ()\nhttps://events.saip.org.za/ev ent/145/contributions/1668/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Bank of Ghana Auditorium URL:https://events.saip.org.za/event/145/contributions/1668/ END:VEVENT BEGIN:VEVENT SUMMARY:The role of X-ray analysis of magic balls for fluoride removal DTSTART;VALUE=DATE-TIME:20190129T154500Z DTEND;VALUE=DATE-TIME:20190129T160000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1669@events.saip.org.za DESCRIPTION:Speakers: Ebenezer Annan (Department of Materials Science and Engineering\, University of Ghana)\nThe role of X-ray analysis of magic ba lls for fluoride removal”\n\nhttps://events.saip.org.za/event/145/contri butions/1669/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1669/ END:VEVENT BEGIN:VEVENT SUMMARY:Investigating lithium vanadium phosphate cathode materials for lit hium- ion batteries DTSTART;VALUE=DATE-TIME:20190131T110000Z DTEND;VALUE=DATE-TIME:20190131T111500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1670@events.saip.org.za DESCRIPTION:Speakers: Michelle Sibonokuhle Nyoni (School of Chemistry\, Un iversity of Witwatersrand\, South Africa)\nSignificant energy demand\, esp ecially on the African continent\, has led to a need in the\ndevelopment o f cost-effective energy storage devices with high performance. Lithium-\ni on batteries have been studied and used extensively due to lithium having one of the\nsmallest ionic radii and the most negative reduction potential \, being lightweight and\nbeing able to achieve a greater energy density a nd power density (Nitta et al.\, 2015).\nThey are highly considered becaus e of their potential to resolve the global warming\nchallenge (Onoda et al .\, 2012). Phosphates have exhibited noteworthy operating\npotentials and high thermodynamic and kinetic stability. Vanadium has the advantage of\nt uning its oxidation state from V 2+ to V 5+ . Combination of these three c omponents\npromises a cathode material that will possibly possess high lit hium capacity\, good ion\nmobility\, a good capacity and a high operating voltage of approximately 4.0 V. Synthesis\nmethods include a solid-state s ynthesis with a combination of grinding and annealing\nunder a hydrogen ga s atmosphere. Techniques useful for characterization of the\ncathode mater ial include powder x-ray diffraction (PXRD)\, thermo-gravimetric analysis\ n(TGA)\, transmission electron microscopy (TEM) and electrochemical testin g that\nincludes galvanostatic charge-discharge\, cyclic voltammetry (CV) and electrochemical\nimpedance spectroscopy (EIS).\n\nhttps://events.saip. org.za/event/145/contributions/1670/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1670/ END:VEVENT BEGIN:VEVENT SUMMARY:Assessment of the O-O bond in terminal dioxygen first row transiti on metal complexes: A CSD/DFT study DTSTART;VALUE=DATE-TIME:20190130T154000Z DTEND;VALUE=DATE-TIME:20190130T160000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1671@events.saip.org.za DESCRIPTION:Speakers: Samuel Tetteh\, (1 Department of Chemistry\, School of Physical Sciences\, College of Agriculture and Natural Sciences\, Unive rsity of Cape Coast\, Cape Coast\, Ghana)\nDioxygen\, a readily available raw material for most oxidation processes\, has been the\nfocus of researc h in inorganic chemistry\, material science and catalysis in recent times. The\nmolecule undergoes multielectron reduction reactions and is used in proton exchange membrane\n(PEM) fuel cell to generate electrical energy. T riplet oxygen is also used in combination with\nphotosensitizers and visib le light to generate singlet oxygen which is employed in photodynamic\nthe rapy (PDT). Other areas of research include the study of biochemical syste ms such as oxygen\ntransport and electron transport using dioxygen complex es of transition metals such as iron and\ncopper in combination with porph yrins. Recently\, vanadium(IV)/(V)-dioxygen complexes are\nbeing explored as insulin mimetics to lower blood sugar levels. In most of thes studies\, FTIR\ndata on increased bond lengths of the coordinated O 2 is largely ex plained by the donation of π-\nelectrons from metal d-orbitals into empty π* ligand orbitals.\nA search in the CSD version 5.39 (November) + 1 upd ate using the ConQuest version\n1.20 software revealed 250 first row trani stion metal complexes with terminal dioxygen ligands.\nThese crystal struc tures were then analysed using mercury 3.10 software of the CCDC.\nStatist ical analysis show strong correlation between O-O bond lengths and O-M-O b ond angles.\nDFT analyses of a vanadium (V)-dioxygen complex (refcode: VEM RUA) and its optimised\nanalogues reveal possible σ-donor\, π-donor weak ening of the O-O bond and not the usual σ-\ndonor\, π-acceptor model use d in explaining this phenomenon.\n\nhttps://events.saip.org.za/event/145/c ontributions/1671/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1671/ END:VEVENT BEGIN:VEVENT SUMMARY:N-Benzyl-4-((heteroaryl)methyl)benzamides :A New Class of Direct N ADH- Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase(InhA) Inhibito rs with Antitubercular Activity DTSTART;VALUE=DATE-TIME:20190130T174000Z DTEND;VALUE=DATE-TIME:20190130T180000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1672@events.saip.org.za DESCRIPTION:Speakers: Koffi Charles Kouman (Laboratoire de Physique Fondam entale et Appliquée)\nWe have carried out a computational structure-based design of new potent N-\nBenzyl-4-((heteroaryl)methyl)benzamides(BHMB) in hibitors of enoyl-acyl carrier protein\n\nreductase (InhA) of Mycobacteriu m tuberculosis (MTb). Three-dimensional (3D) models of\nInhA-BHMBx complex es were prepared by in situ modification of the crystal structure of\nInhA -BHMB1 (Protein Data Bank (PDB) entry code: 4QXM)\, the reference compound of a\ntraining set of 19 BHMBs with known experimental inhibitory potenci es (IC50\n\nexp). First\, we\nbuilt a gas phase quantitative structure-act ivity relationships (QSAR) model\, linearly\ncorrelating the computed enth alpy of the InhA-BHMB complex formation and the IC50\nexp\n.\nFurther\, ta king into account the solvent effect and loss of inhibitor entropy upon en zyme\nbinding led to a QSAR model with a superior linear correlation betwe en computed Gibbs free\nenergies (∆∆Gcom) of InhA-BHMB complex formati on and IC50\nexp (pIC50\nexp = -0.237∆∆Gcom +\n\n7.8783\, R\n2 = 0.97) \, which was further validated with a 3D-QSAR pharmacophore model\ngenerat ion (PH4).\n\nhttps://events.saip.org.za/event/145/contributions/1672/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1672/ END:VEVENT BEGIN:VEVENT SUMMARY:Thermoresponsive behaviour of (NH4)0.5Co1.25(H2O)2[BP2O8].(H2O)0.5 with CZP framework topology DTSTART;VALUE=DATE-TIME:20190129T154500Z DTEND;VALUE=DATE-TIME:20190129T160000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1673@events.saip.org.za DESCRIPTION:Speakers: Mashikoane Mogodi (European Synchrotron Radiation Fa cility (ESRF))\nKeywords: borophosphates\, high-temperature\, dehydration\ , thermal-induced amorphisation\, in-\nsitu synchrotron XRPD\n\nTheme: Cry stal Engineering and Structural Chemistry\nFour CZP (chiral zincophosphate ) zeolite topology compounds [1] with the general formula\nMIMII (H2O)2[BP 2O8].yH2O (MI = Na\, NH4 and MII = Mn\, Co\, y = 0.5\, 1) have been prepar ed\nunder mild hydrothermal conditions (at 180 °C). Such microporous comp ounds with\naesthetically interesting crystal structures can have interest s in fields such as catalysis\, storage\,\nseparation and ion-exchange. On e compound of this family\,\n(NH4)0.5Co1.25(H2O)2[BP2O8].(H2O)0.5\, has be en studied by variable temperature high resolution\npowder X-ray diffracti on\nexperiments carried out from 298 to\n1073 K. Complete Rietveld\nrefine ments were achieved by\ncombining stereochemical restraints\nwith the powd er diffraction data. At\nroom temperature\, this compound\ncrystallizes in the P65 (No. 170)\nspace group with Z = 4 belonging to\nthe hexagonal sys tem. The unit cell\nparameters obtained were: a = 9.4330(2) Å\, c = 15.52 03(2) Å\, V = 1196.01(5) Å\n3\n. This\nreciprocal space analysis also re vealed the presence of positional disorder via large refined\nMSDs. The cr ystal structure consists of a helical anionic framework\, ∞[BP2O8]\n3-\n \, composed of\ncorner sharing BO4 and PO4 tetrahedra. Water and ammonia m olecules are found within the\nhelical channels running along the [001] di rection. This compound undergoes a series of\ndehydration\, de-ammoniation (analysis augmented by thermogravimetric experiments and\nFourier analysi s) and finally long range structural decomposition into an amorphous phase .\nTotal scattering analysis [2] was applied for the first time coupled to the above conventional\nstructural refinement approach to map the identif ied positional disorder into real space\, and to\nfurther unravel the gase ous dissociation and subsequent decomposition pathway of the rigid\nhost s tructure.\n\nhttps://events.saip.org.za/event/145/contributions/1673/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1673/ END:VEVENT BEGIN:VEVENT SUMMARY:Practical 3 : Imaging/harvesting DTSTART;VALUE=DATE-TIME:20190128T170000Z DTEND;VALUE=DATE-TIME:20190128T193000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1698@events.saip.org.za DESCRIPTION:Speakers: M Nidi (Unkown)\, RIchard Garratt (University of Sã o Paulo)\nhttps://events.saip.org.za/event/145/contributions/1698/ LOCATION:Bank of Ghana Conference Facility\, University of Ghana. URL:https://events.saip.org.za/event/145/contributions/1698/ END:VEVENT BEGIN:VEVENT SUMMARY:President of Ghana DTSTART;VALUE=DATE-TIME:20190129T083000Z DTEND;VALUE=DATE-TIME:20190129T084500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1699@events.saip.org.za DESCRIPTION:https://events.saip.org.za/event/145/contributions/1699/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1699/ END:VEVENT BEGIN:VEVENT SUMMARY:Practical 1 : Remote data collection lecture and practicals DTSTART;VALUE=DATE-TIME:20190128T113000Z DTEND;VALUE=DATE-TIME:20190128T133000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1700@events.saip.org.za DESCRIPTION:Speakers: Ralf Flaig (Diamond Light Source Ltd.)\nhttps://even ts.saip.org.za/event/145/contributions/1700/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Amissah- Arthur Hall URL:https://events.saip.org.za/event/145/contributions/1700/ END:VEVENT BEGIN:VEVENT SUMMARY:Development of a pelvic prosthesis phantom using 3D printing techn ology for the radiotherapy dosimetry of cancer patients with hip Ti prosth eses DTSTART;VALUE=DATE-TIME:20190129T164000Z DTEND;VALUE=DATE-TIME:20190129T164500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1676@events.saip.org.za DESCRIPTION:Speakers: Nicholas Ade (University of the Free State\, Bloemfo ntein\, SA)\nRadiotherapy is a well-established treatment modality for pel vic lesions. Hip replacement is a surgical procedure in which the hip join t is replaced by a prosthetic implant. During irradiation of malignancies in the hip or pelvic region with external megavoltage beams\, the presence of metallic prostheses complicates dosimetry and treatment delivery due t o the dose perturbation effect of high-Z materials in radiation fields. Th is work describes a novel pelvic prosthesis phantom that was developed usi ng 3D printing technology for studies involving the dosimetry of patients with hip Ti prostheses. The phantom is made out of water-equivalent Nylon- 12 layers and is equipped with unilateral hip Ti prosthesis and the bony s tructures of the pelvis and lower abdomen. Dose perturbations caused by th e Ti implant were studied using Gafchromic film measurements in 10 × 10 c m2 15 MeV electron and 10 MV photon beams. At the interface between tissue and metal on the beam entry side of the prosthesis\, dose enhancements of about 10% and 25% were recorded for the 15 MeV and 10 MV beams\, respecti vely. On the beam exit side of the prosthesis\, the 10 MV photon beam was attenuated by 17% which would lead to a dose reduction at the target. A do simetric error of 1025% caused by prostheses could influence treatment outcome. This study shows that using 3D printing technology\, very complex phantoms can be developed for the radiotherapy dosimetry of patients with metallic implants. The novelty of the presented phantom for dose perturba tion studies is that it reflects clinical irradiation setups better than u sing simplified phantom geometries which may differ considerably from real patient cases.\n\nhttps://events.saip.org.za/event/145/contributions/1676 / LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1676/ END:VEVENT BEGIN:VEVENT SUMMARY:The Study of the Residual stresses and Wear performance of WC-Co t hin film deposition by Magnetron Sputtering DTSTART;VALUE=DATE-TIME:20190129T172500Z DTEND;VALUE=DATE-TIME:20190129T173000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1677@events.saip.org.za DESCRIPTION:Speakers: L.L. Collieus (Botswana International University of Science and Technology)\nControl and manipulation of residual stresses in thin films is key in attaining coatings with high mechanical and tribo-log ical performance. This work\, therefore\, focused on investigating residua l stresses generated in WC-Co thin film coatings\, deposited on mild steel substrates by magnetic sputtering. The effect of deposition parameters on the generation of these stresses was analyzed on the thin film coating by sin 2ψ X-ray diffraction. The X-ray spectra of the surface revealed an a morphous phase of the thin film\, as a result\, the measured stresses were of the substrate surface. Compressive stresses were identified within all samples studied. These compressive stresses are mainly attributed to the atomic shot peening of the surface during deposition\, which was observed to be greatly influenced by sputtering parameters. Investigation was furth er extended to study the wear performance of the coating which was remarka ble compared to the as-received substrate.\n\nhttps://events.saip.org.za/e vent/145/contributions/1677/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1677/ END:VEVENT BEGIN:VEVENT SUMMARY:One million structures to power chemical science DTSTART;VALUE=DATE-TIME:20190130T143000Z DTEND;VALUE=DATE-TIME:20190130T150000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1678@events.saip.org.za DESCRIPTION:Speakers: Amy A Sarjeant (The Cambridge Crystallographic Data Centre\, Princeton NJ\, USA)\nFor over 50 years\, the Cambridge Crystallog raphic Data Centre (CCDC) has been curating the\nworld’s small molecule crystal structures into the Cambridge Structural Database (CSD). This\ncol lection has grown steadily through the years and is now poised to reach 1 million structures.\nFar more than just a collection of crystal structures \, the data in the CSD provide the fuel that\ndrives scientific discovery across diverse areas of research. This presentation will focus on a\nnumbe r of research projects that incorporate the software tools that harness th e power of the\nCSD. We will look at methods that explore the crystallogra phic solid form of small molecules\nby elucidating intermolecular interact ion networks\, from hydrogen to halogen bonding\, assessing\nthe risk of p olymorphism and understanding molecular geometries.\n\nhttps://events.saip .org.za/event/145/contributions/1678/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1678/ END:VEVENT BEGIN:VEVENT SUMMARY:Influence of hydrogenation on residual stresses in oxygen-implante d Ti-6Al-4V alloy DTSTART;VALUE=DATE-TIME:20190129T173000Z DTEND;VALUE=DATE-TIME:20190129T173500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1679@events.saip.org.za DESCRIPTION:Speakers: Schadrack Nsengiyumva (Rhodes University)\nThe influ ence of hydrogenation on residual stresses in oxygen-implanted Ti-6Al-4V a lloy is reported. Prior to hydrogenation\, oxygen ions were implanted in T i-6Al-4V samples at fluence 3x1017 ions/cm2 with energies 50 keV at room t emperature and 5500C\, 100 keV and 150 keV at 5500C. Hydrogenation was car ried out on all samples at 5500C for two hours. Residual stresses were ana lysed by X-ray diffraction using the sin2 in conjunction with LEPTOS v6 data reduction. Our results show stress relaxation in samples implanted with 50 keV and 100 keV with respect to unimplanted sample. However\, samp les implanted with 150 keV show tensile stress state. Subsequent to hydrog enation\, a change in stress for samples implanted with 50 keV and 100 keV is observed whereas stress in samples implanted with 150 keV becomes more tensile.\n\nhttps://events.saip.org.za/event/145/contributions/1679/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1679/ END:VEVENT BEGIN:VEVENT SUMMARY:Building the future: sustainability of construction materials DTSTART;VALUE=DATE-TIME:20190131T113000Z DTEND;VALUE=DATE-TIME:20190131T120000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1680@events.saip.org.za DESCRIPTION:Speakers: Gilberto Artioli (Università di Padova\, Dipartimen to di Geoscienze\, Padova\, Italy)\nModern trends in frontier materials sc ience are commonly related to finding and characterizing\nsuitable materia ls for advanced and innovative technological applications. However\, even in the\nfield of materials that are commonly considered “low-tech” suc h as construction materials and\nbinders\, there are a number of open\, ti mely\, and rather challenging issues to be confronted. Possibly\nthe most urgent and crucial problem is the sustainability character of materials us ed to build human\ninfrastructures: bricks\, structural ceramics\, concret e\, advanced binders\, insulation materials. Cement\nand concrete at prese nt are the most used materials after water\, and it is clear that modern b uildings\nand infrastructures are critically dependent on such materials. The volume of annual word\nproduction of concrete\, in the order of 10 10 tons and growing\, exceeds the volume of consumed fuels\n(oil and coal).\n The fundamental concept of circular economy in the anthropocene era [ 1 ] demands that the use and\nmisuse of natural and man-made mass-produced mat erials ought to be linked not only to the\nartificial loops dominated by f inance-based economy\, which is now the dominating parameter\, but\nrather to the evaluation of the sustainability and the life cycle assessment of the resources [ 2 ].\nAdoption of the R3 philosophy (reduce\, reuse\, recy cle) is simply mandatory.\nThese concepts will be discussed in relationshi p to present trends in cement and concrete\nproduction. Promising cements and binders alternative to Portland clinker are based on (a) clay-\nbased materials\, (b) alkali activated materials\, and (c) the so-called geopoly mers. The advantages\nand disadvantages of these novel materials are discu ssed. The knowledge-based selection of\nmaterials and their optimization i n large-scale productive processes is extremely important both for\ndevelo ped and developing economies [ 3 \, 4 ].\n\nhttps://events.saip.org.za/eve nt/145/contributions/1680/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1680/ END:VEVENT BEGIN:VEVENT SUMMARY:Practical 2 : Protein Crystallization DTSTART;VALUE=DATE-TIME:20190128T143000Z DTEND;VALUE=DATE-TIME:20190128T170000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1701@events.saip.org.za DESCRIPTION:Speakers: Emmanuel Nji (University of Stockholm\, Sweden)\, M Nidi (Unkown)\nhttps://events.saip.org.za/event/145/contributions/1701/ LOCATION:Bank of Ghana Conference Facility\, University of Ghana. URL:https://events.saip.org.za/event/145/contributions/1701/ END:VEVENT BEGIN:VEVENT SUMMARY:Minister of Environment\, Science\, Technology and Innovation DTSTART;VALUE=DATE-TIME:20190129T084500Z DTEND;VALUE=DATE-TIME:20190129T090000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1702@events.saip.org.za DESCRIPTION:https://events.saip.org.za/event/145/contributions/1702/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1702/ END:VEVENT BEGIN:VEVENT SUMMARY:UNESCO DTSTART;VALUE=DATE-TIME:20190129T090000Z DTEND;VALUE=DATE-TIME:20190129T091000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1703@events.saip.org.za DESCRIPTION:Speakers: Jean Paul Ngome (N/A)\nhttps://events.saip.org.za/ev ent/145/contributions/1703/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1703/ END:VEVENT BEGIN:VEVENT SUMMARY:Lanthanide-transition metals molecular materials: Synthesis and C rystal structure. DTSTART;VALUE=DATE-TIME:20190130T121500Z DTEND;VALUE=DATE-TIME:20190130T123000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1681@events.saip.org.za DESCRIPTION:Speakers: Mamoudou Diallo (LCPM―Groupe ‘’Matériaux Inor ganiques: Chimie Douce et Cristallographie’’\, Université Assane Sec k de Ziguinchor\, BP 523 Ziguinchor\, Sénégal)\nKnowledge about molecula r materials structures combined with chemical crystallography concepts has always helped the chemist to understand the solid formation from some ent ities\nand consequently stirred his imagination for the construction of ne w varying combinations. However\, the growth of a pure\, well-shaped and s ufficient size single crystal remains a challenge. The study of materials with structures consisting of metal centers that are linked into extended networks by bridging organic ligands is an important and growing area of m odern chemistry [ 1 ] . Our work consisted in synthesizing through slow di ffusion gel media [ 2 ] \, new tridimensional heterometallic molecular mat erials difficult\, if not impossible\, to obtain by conventional methods. A new family of isostructural compounds crystallizing in the triclinic sys tem (space group P-1) has been obtained. The structure is composed of dinu clear chains sandwiching oxalate ligands. The three-dimensional network is ensured by hydrogen bonds O-H---O of water molecules assisted by π-π* s tacking interactions [3] . A concern underlying the chemical interest of t hese coordination complexes will be the search for interesting physical pr operties that could lead to potential applications.\n\nhttps://events.saip .org.za/event/145/contributions/1681/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1681/ END:VEVENT BEGIN:VEVENT SUMMARY:Luminescent materials for enhanced silicon solar cell performance DTSTART;VALUE=DATE-TIME:20190129T170000Z DTEND;VALUE=DATE-TIME:20190129T171500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1682@events.saip.org.za DESCRIPTION:Speakers: Mubarak Yagoub (University of the Free State)\nLanth anide-based luminescent nano-materials have been extensively investigated due to their contribution to a different range of applications. The use of lanthanide ions for enhancing the solar cell efficiency has recently been reported. Silicon based solar cells show a poor response to UV–blue ran ge of the solar spectrum. This limits the crystalline silicon (c-Si) solar cell efficiency to only 30%\, according to detailed balance model develop ed by Shockley-Queisser. The thermalization of the charge carriers is one of the major loss mechanisms\, which could be overcome by deposit a down-c onverting layer on top of the c-Si solar cell. This phenomenon has recentl y been reported in Pr3+—Yb3+ couple doped materials. Unfortunately\, the weak absorption cross-section of the 4f-4f transition of Pr3+ ion prevent ing absorption of the larger part of the solar spectrum. For efficient do wn-conversion it is crucial that the major part of the high energy region of the solar spectrum is converted into two near-infrared photons. Therefo re\, a third sensitizer that can absorb efficiently all light in the UV-bl ue part of the solar spectrum and transfers the energy to the down-convers ion couple\, e.g. 3Pj levels of Pr3+ is required. Recent theory has predic ted that by applying such down-conversion layer on top of the c-Si solar c ell\, the Shockley-Queisser limit could be raised up to 40%. This study re ports on the application of rare-earth-doped inorganic materials for achie ving external quantum efficiencies greater than unity and enhancing the co nversion efficiency of silicon solar cells by using the down-conversion me chanism.\n\nhttps://events.saip.org.za/event/145/contributions/1682/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1682/ END:VEVENT BEGIN:VEVENT SUMMARY:Heterotrinuclear complex of (Ni-K-Ni) and Co-crystal structure of a dinuclear (Zn-Y) and a trinuclear (Zn-Y-Zn) DTSTART;VALUE=DATE-TIME:20190130T163000Z DTEND;VALUE=DATE-TIME:20190130T164500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1683@events.saip.org.za DESCRIPTION:Speakers: Ibrahima Elhadji THIAM (Department of Chemistry\, Un iversity Cheikh Anta Diop\, Dakar\, Senegal)\nThe very dynamic field of re search for the design and synthesis of heteropolynuclear\ncomplexes of d a nd f-block elements has made it possible to generate original structures w ith\ninteresting properties in various fields such as magnetism\, optics\, catalysis and luminescence.\nThe present investigation describes the synt hesis and structural study of two complexes.\nThe complex 1 is a Heterotri nuclear complexes synthesis which was used to generate three\ndimensional complexes formulated as [{Ni(L)}(K){Ni(L)}](SCN). The compound crystallize s\nin the Monoclinic system Space group P2 1 /c with the following unit ce ll dimensions a =\n11.5891(13) Å b = 17.307(2) Å c = 19.781(2) Å and b= 92.368(10)°\, R1= 0.1172. In the\ncompound the ligand H 2 L is hexadenta te. In the unit the coordination environment of the Ni\nmetal can be descr ibed as distorted square\, the alkaline metal K is octacoordinated.\nThe c omplex 2 is a co-crystal which was a three dimensional supramolecular comp lexs.\nformulated as [Y{Zn(L)(SCN)}(SCN) 2 ].[Y{Zn(L)(SCN)} 2 (DMF) 2 ].(N O 3 ). It crystallizes in\nthe triclinic space group P-1 with unit cell pa rameters: a = 14.8987(7) Å\, b = 15.6725(8) Å\, c\n= 19.2339(10) Å\, α = 94.610(4)°\, β = 103.857(4)°\, γ = 101.473(4)°\, R1 = 0.063.\nHete rodinuclear unit [Y{Zn(L)(SCN)}(SCN) 2 ] is co-crystallized with a heterot rinuclear unit\n[Y{Zn(L)(SCN)} 2 (DMF) 2 ].(NO 3 ). In the dinuclear moiet y\, the ligand is hexadentate and in the\ntrinuclear unit\, it is pentaden tate with one of the oxygen methoxy group remaining\nuncoordinated. The co ordination environment Zn metal is square pyramidal. In the dinuclear\nuni t the Y(III) is hexacoordinated while it is octacoordinated in the trinucl ear unit. The\nenvironment of the Y(III) can be described as a distorted o ctahedral geometry in the dinuclear\nand as a distorted square antiprism i n the trinuclear units respectively.\n\nhttps://events.saip.org.za/event/1 45/contributions/1683/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1683/ END:VEVENT BEGIN:VEVENT SUMMARY:Crystalline Phase Stabilization and Structure Dynamics of Oxide-io n Conducting Bismuth Oxides Doped with Rare–earth Cations DTSTART;VALUE=DATE-TIME:20190130T164500Z DTEND;VALUE=DATE-TIME:20190130T170000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1684@events.saip.org.za DESCRIPTION:Speakers: Tumaini Mkwizu (University of the Witwatersrand)\nTh e interconnection between structural and charge–transport properties of crystalline oxide systems\, particularly\, towards their potential applica tions in solid oxide fuel cells (SOFCs) and solid oxide electrolysis cells (SOECs) and related energy conversion devices\, is increasingly becoming important in the 21st century as the global requirements for sustainable a nd technologically efficient renewable energy systems continue to rise [1\ , 2]. In particular\, facile charge transport involving mobile oxide ions (O2–) in potential phase–tuned solid electrolytes is essential for rob ust energy cycles in SOFCs and SOECs tweaked to operate at intermediate an d low temperature regimes (~600 °C down to room temperature) [2–4]. Bis muth–based oxides are of great interest due to the highest O2– conduct ivity observed in the δ–Bi2O3 phase (with face–centred cubic defect f luorite structure) [5]. Various rare–earth doped CeO2 systems have inter esting solid state charge–transport properties attributable to distortio ns of the fluorite crystal lattice [6]. In this work\, single– and doubl e–doped bismuth oxides (with Gd3+ and Ce4+ as substituent cations for Bi 3+) were prepared via synthetic manipulations involving citrate–nitrate decomposition reactions in acetic acid medium using metal nitrate precurso r salts and citric acid as a complexing agent. Room temperature stable pha ses were studied upon calcination at 400 °C and additional heat treatment (up to 850 °C). Phase stability and transformation studies were undertak en using powder X–ray diffraction (PXRD) performed ex situ (room tempera ture) and in situ (variable temperature (VT) up to ~850 °C). Phase identi fications and crystal structure determinations were pursued within the fra mework of Rietveld refinement from powder diffraction data [7]. Insights o n structure–composition–property relations (as a function of temperatu re) were gained from case studies of doped oxides employed as solid electr olytes for alternating current conductivity measurements involving electro chemical impedance spectroscopy.\n\nReferences:\n1. Azizi\, M. A.\, and Br ouwer\, J.\; Applied Energy\, 2018\, 215\, 237–289.\n2. Wachsman\, E.D. and Lee\, K.T.\; Science.\, 2011\, 334\, 935–939.\n3. Minh\, N. Q.\, Mog ensen\, M. B.\; Electrochem. Soc. Interface\, 2013\, 22\, 55–62.\n4. Mah ato\, N.\, Banerjee\, A.\, Gupta\, A.\, Omar\, S.\, and Balani\, K.\; Prog r. \nMater. Sci.\, 2018\, 72\, 141–337.\n5. Drache\, M.\, Roussel\, P.\, and Wignacourt\, J.P.\; Chem. Rev.\, 2007\, 107\, 80–96.\n6. Omar\, S.\ , Wachsman\, E. D.\, Jones\, J. L.\, Nino\, J. C.\; J. Am. Ceram. Soc.\,20 09\, 92\, 2674–2681.\n7. Coelho\, A.A.\; J. Applied Cryst.\, 2018\, 51\, 210–218.\n\nhttps://events.saip.org.za/event/145/contributions/1684/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1684/ END:VEVENT BEGIN:VEVENT SUMMARY:IUCr-UNESCO OpenLab DTSTART;VALUE=DATE-TIME:20190130T171000Z DTEND;VALUE=DATE-TIME:20190130T173000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1685@events.saip.org.za DESCRIPTION:Speakers: Michele Zema (International Union of Crystallography )\nThe worldwide nature of the UN International Year of Crystallography 20 14 has provided new opportunities to develop educational activities at all levels in parts of the world where crystallography is as yet a poorly dev eloped science\, and to set in motion new initiatives in capacity building and international cooperation. In this regard and to stimulate curriculum development\, the IUCr and UNESCO have set up the OpenLab project\, a net work of operational crystallographic laboratories in selected universities in Africa\, Latin America and Southeast Asia\, as a practical start in ad dressing such training requirements. As of today\, over 25 OpenLabs have b een organized\, which provided high-level educational opportunities to ove r a thousand local students and young professors\, taking advantage of the synergic combination of scientific and educational expertise of the IUCr\ , diplomatic and educational channels of UNESCO\, and partnership of cryst allographic instrumentation manufacturers. Part of this project is closely connected with the “Crystallography in Africa” initiative of the IUCr \, thanks to which crystallographic equipment has been recently installed or is being installed in some sub-Saharan African countries. The project i s now evolving towards an extended network of collaborations\, which inclu de other scientific bodies\, such as IUPAP and ICTP\, and it serves as one of the main educational tools within the IUPAP-IUCr LAAAMP project.\n\nht tps://events.saip.org.za/event/145/contributions/1685/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1685/ END:VEVENT BEGIN:VEVENT SUMMARY:Development of Compton compact X ray sources DTSTART;VALUE=DATE-TIME:20190128T160000Z DTEND;VALUE=DATE-TIME:20190128T163000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1686@events.saip.org.za DESCRIPTION:Speakers: Kevin Dupraz (CNRS / LAL)\nCompact high flux x-ray s ources can be obtained thanks to Laser-electron beam Compton scattering [1 ]. Some Compton x-ray sources and related R&D activities are presently und er development. Starting from the Lyncean commercial fully operational sma ll and compact electron ring [2] other projects aiming to reach higher x r ay energy\, higher flux or higher compactness have been launched worldwide \, e.g.: Smartlight [3]\, STAR [4]\, ThomX [5] and TTX[6]. Whereas Smartli ght\, Star and TTX are based on LINAC technologies\, ThomX is an electron ring of 50MeV-70MeV (a similar project TTX2 in under design study in China [7]). \nIn this presentation we shall concentrate on two topics. The stat us and expected performances of the ThomX machine will first be given. Iss ues and limits of the related laser system will also be discussed. Second\ , a possible upgrade of the STAR project making use of an optimization of the recently demonstrated burst regime of optical resonators [8] will be d escribed. Optimization of the burst mode will be explained together with a n estimate of x ray flux for such LINAC based Compton machine. \n [1] Fede rici L\, Giordano G\, Matone G\, et al. Backward Compton scattering of las er light against high-energy electrons: the LADON photon beam at Frascati. Il Nuovo Cimento B 59(1980)247–256\n[2] Gradl et al.\, Scientific Repor ts 8\, 6788 (2018)\n[3] Luiten\, O. J. (2016). KNAW-Agenda Grootschalige O nderzoeksfaciliteiten : Smart*Light: a Dutch table-top synchrotron light s ource. Amsterdam: Koninklijke Nederlandse Akademie van Wetenschappen (KNAW ).\n[4] A. Bacci et al.\, in Proceedings\, 7th International Particle Acce lerator Conference (IPAC 2016): Busan\, Korea\, May 8-13\, 2016 (2016) p. TUPOW004.\n[5] P. Walter et Al.\, C.R. Physique \n[6] Tang C\, Huang W\, L i R\, et al. Tsinghua Thomson scattering X-ray source. Nuclear Instruments and Methods in Physics Research Section A: Accelerators\, Spectrometers\, Detectors and Associated Equipment\, 2009\, 608(1)\n[7] H.S. Xu et al.\, Phys. Rev. STAB 17(2014) 070101\n[8] K. Sakaue et Al.\, Review of Scientic Instruments 89\, 023305 (2018)\n\nhttps://events.saip.org.za/event/145/co ntributions/1686/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1686/ END:VEVENT BEGIN:VEVENT SUMMARY:The Extremely Brilliant Source at the ESRF DTSTART;VALUE=DATE-TIME:20190201T141500Z DTEND;VALUE=DATE-TIME:20190201T144500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1687@events.saip.org.za DESCRIPTION:Speakers: Francesco Sette (European Synchrotron Radiation Faci lity (ESRF))\nThe ESRF Upgrade Programme\, started in 2009\, and developed in two phases\, is delivering a new\ngeneration of beamlines and a new X- ray source with qualitatively improved performances compared to\nwhat is a vailable today.\nWith drastically increased brightness and coherence\, the soon-coming ESRF Extremely Brilliant Source\n(EBS) will open new opportun ities for synchrotron users. I will review recent progress in the construc tion\nand implementation of the EBS programme.\n\nhttps://events.saip.org. za/event/145/contributions/1687/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1687/ END:VEVENT BEGIN:VEVENT SUMMARY:Structural changes of swift heavy ion irradiated spark plasma sint ered ZrC/SiC solid solution DTSTART;VALUE=DATE-TIME:20190129T153000Z DTEND;VALUE=DATE-TIME:20190129T154500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1688@events.saip.org.za DESCRIPTION:Speakers: Saphina Biira (Busitema University Uganda)\nHigh tem perature nuclear reactors use TRISO (tristructural isotropic) fuel particl es for\ncontainment of radioactive fission products. TRISO particles consi st of uranium oxide coated\nuniformly with low density pyrocarbon\, high d ensity inner pyrocarbon\, silicon carbide (SiC)\, and\ndense outer pyrocar bon. In these particles\, SiC is the main barrier for containing solid fis sion\nproducts. These particles retain most fission products with the exce ption of silver\, europium at\ntemperatures below 1000 °C. It has been su ggested that it would be advantageous to add a thin\nZrC layer (in additio n to the normal SiC layer) or replace SiC layer with ZrC. This is because\ nZrC has a high melting temperature of 3540 °C\, low neutron capture cros s section\, corrosion\nresistance to fission products\, relatively low den sity\, excellent thermal stability and high\nhardness. There are few studi es on the irradiation resistance of ZrC and ZrC/SiC that have been\nreport ed. This study investigates the effects of swift heavy ions on the structu ral changes of spark\nplasma sintered ZrC/SiC solid solutions.\nThe micros tructure changes of spark plasma sintered ZrC/SiC solid solution irradiate d by swift\nheavy ions at different fluences from 10 12 to 3×10 14 ion/cm 2 at room temperature were studied\nusing the synchrotron-based X-ray dif fraction (XRD) characterisation. The surface morphology\nof the ZrC/SiC sa mples was analysed using an ultrahigh resolution field-emission scanning\n electron microscopy (FE-SEM\, Zeiss Ultra Plus). Raman spectroscopy was al so used to study\nchanges in vibration modes of the ZrC/SiC structure. The synchrotron-based XRD results showed that as the Xe 26+ ion fluences incr eased during irradiation\, the peaks of the XRD pattern broadened and shif ted to the left. This is an indication of crystal structure distortion and strain in the material. The crystallize size and the volume of the lattic e changed with change in ion fluences. The changes in the surface morpholo gy with ion fluences were not very significant. The evolution of free carb on was observed to decrease in the samples as the ion fluencies decreased. This means that there was some level of crystallization and structural re arrangement of the material. The detailed discussion of the structural cha nges of the irradiated ZrC/SiC samples at different ion fluences will be p resented in the paper.\n\nhttps://events.saip.org.za/event/145/contributio ns/1688/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1688/ END:VEVENT BEGIN:VEVENT SUMMARY:XAFS as a tool to obtain chemical states and local structures DTSTART;VALUE=DATE-TIME:20190131T112500Z DTEND;VALUE=DATE-TIME:20190131T115000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1689@events.saip.org.za DESCRIPTION:Speakers: Hitoshi Abe (Photon Factory (PF)\, Institute of Mate rials Structure Science (IMSS)\, High Energy Accelerator Research Organiza tion (KEK))\nX-ray Absorption Fine Structure (XAFS) is one of the most wid ely used methods at synchrotron facilities. XAFS is a suitable nondestruc tive method to observe chemical states elements and local structures aroun d elements of interest in not only crystalline or solid but also amorphous or liquid samples. From a crystallographic point of view\, If we have cr ystalline samples\, it's good to perform XRD experiments to obtain informa tion on crystal structures. When we are\, however\, interested in local structures of a certain element in a sample\, XAFS can be a powerful tool. In other words\, XAFS can provide complementary information to XRD.\nWe would like to share some XAFS studies.\n\nhttps://events.saip.org.za/event /145/contributions/1689/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1689/ END:VEVENT BEGIN:VEVENT SUMMARY:Refractory bricks worked out with raw materials from Burkina Faso: effect of the nature of grog and the alumina contents in the mineral bind er DTSTART;VALUE=DATE-TIME:20190131T120000Z DTEND;VALUE=DATE-TIME:20190131T121500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1690@events.saip.org.za DESCRIPTION:Speakers: Moustapha SAWADOGO (Université Ouaga)\nThe purpose of this work is to study the influence of the nature of the grog and the b inder on the properties of refractory bricks worked out through clays from Burkina Faso. Then\,\ntwo natural clays and sand were characterized to wo rk out refractory bricks. The characterization by Chemical analysis and X- ray diffraction indicates that these clays\, called SAB and TIK\, present the same mineral phases but with various contents. Sample TIK has an alumi na content higher than SAB. One of these clays\, SAB\, was extruded then w as sintered at 1300 °C with a bearing of 1 hour to produce grog. Bricks w ere worked out by pressing of mixtures of raw clays and grog\, also of raw clays and sand. Then they were under 2 hours sintering at four different temperatures (1250\, 1300\, 1350 and 1400 °C). The analyses showed that f rom 1350 °C\, brick obtained by the mixture of SAB and grog\, presents go od physicochemical\, mineralogical and\nthermal properties with a temperat ure of initial softening higher than 1387 °C.\n\nhttps://events.saip.org. za/event/145/contributions/1690/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1690/ END:VEVENT BEGIN:VEVENT SUMMARY:The impact of the Brazilian synchrotron initiative (UVX and SIRIUS ) on the scientific development of Brazil - Protein Crystallography as an example DTSTART;VALUE=DATE-TIME:20190128T120000Z DTEND;VALUE=DATE-TIME:20190128T123000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1691@events.saip.org.za DESCRIPTION:Speakers: RIchard Garratt (University of São Paulo)\nProtein crystallography in Brazil really took off in the late 1980s and had its or igins in São Carlos\, where a group of small-molecule crystallographers w as already well established. At that time it was necessary to overcome the skepticism of the scientific community who perceived protein crystallogra phy to be an overly complex and sophisticated discipline for the existing infrastructure and knowhow. However\, at about the same time\, the first s teps were also being taken in the construction of a synchrotron light sour ce at Campinas in the state of São Paulo. This proved to be a critical in gredient because the presence of the synchrotron provided the catalysis fo r growing the PX community\, which is now widespread and thriving througho ut the country. Nevertheless the building of the first low-energy machine (UVX) also initially required overcoming significant skepticism. A second machine is now close to\ncompletion and promises to offer first-rate facil ities for frontier research in Latin America. Is the user community prepar ed?\n\nhttps://events.saip.org.za/event/145/contributions/1691/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryetey Hall URL:https://events.saip.org.za/event/145/contributions/1691/ END:VEVENT BEGIN:VEVENT SUMMARY:Understanding Complex Metal Hydrides via Synchrotron X-ray Studies DTSTART;VALUE=DATE-TIME:20190130T114500Z DTEND;VALUE=DATE-TIME:20190130T120000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1692@events.saip.org.za DESCRIPTION:Speakers: Tabbetha Dobbins (Rowan University)\nOur research us es several specialized synchrotron X-ray techniques to elucidate the inter actions between transition metal salts additives and hydride host structur es. The presentation will describe those techniques and their use in desc ribing the physical and chemical processes occurring between the hydrides and catalysts.\n\nhttps://events.saip.org.za/event/145/contributions/1692/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1692/ END:VEVENT BEGIN:VEVENT SUMMARY:BAMline 2.0 – further technical developments for a broader multi purpose hard X-ray beamline @ BESSY II (Berlin\, Germany) DTSTART;VALUE=DATE-TIME:20190130T153000Z DTEND;VALUE=DATE-TIME:20190130T154500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1693@events.saip.org.za DESCRIPTION:Speakers: Kirill Yusenko (Bundesanstalt für Materialforschung und -prüfung (BAM))\nThe BAMline was the first hard X-ray beamline being installed at BESSY II in 2001 [1]. Owed to a 7 Tesla wavelength shifter ( WLS) installed at the electron storage ring\, a continuous broad energetic spectrum up to 100 keV is achieved. The available analytical methods fall into the three main groups: X-ray fluorescence spectroscopy (XRF)\, X-ray absorption spectroscopy (XAS) and X-ray computed tomography (CT).\nAn upg rade of this beamline is being currently carried out. The purpose is to ac hieve a broader range of analytical possibilities for questions regarding catalysis\, ‘green chemistry’\, material\, biology\, medicine or envir onment.\nAt the moment the double multilayer monochromator (DMM) consists of alternating layers of W/Si with an intrinsic energy bandwidth of 2.3 %. Although the reflectivity is high up to 50 keV\, there is a sudden drop b etween 10-13 keV due to absorption of tungsten L-lines. This hinders appli cations\, which deal with elements in this energy range. In order to overc ome this\, a multistripe coating DMM is being developed. Furthermore\, one of the coatings is planned for a broader energy bandwidth\, which is esse ntial for applications that require a polychromatic beam in a single shot. \nThe properties of these coating are summarized in table 1. A detailed ex planation with concrete examples of applications will be presented.\n\nTab le 1 – Multistripe properties\nStripe 1 2 3\nLayer structure Periodic Single Per iodic\nLayer Mo/B4C Pd W/Si\nPeriodic thickness d 2.9 nm 30 nm 2.9 nm\nГ 0.4 - 0.4\nNumber of bilayers 300 - 200\nOptimal energy range 5-16 keV - 5-10 keV\n 15-60 keV\nBandwidth ( @ 8 keV) ~1.3 % Total reflection ~3 %\n\nReferences\n[1] W. Goern er et al. BAMline: the first hard X-ray beamline at BESSY II. Nuclear Inst ruments and Methods in Physics Research A 467–468 (2001) 703–706.\n\nh ttps://events.saip.org.za/event/145/contributions/1693/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1693/ END:VEVENT BEGIN:VEVENT SUMMARY:Light Sources and Developing Countires DTSTART;VALUE=DATE-TIME:20190201T112500Z DTEND;VALUE=DATE-TIME:20190201T114500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1694@events.saip.org.za DESCRIPTION:Speakers: Sekazi Mtingwa (Massachusetts Institute of Technolog y &\; Brookhaven National Laboratory&\; African Laser Centre)\nhttps ://events.saip.org.za/event/145/contributions/1694/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1694/ END:VEVENT BEGIN:VEVENT SUMMARY:Pre Conference Workshop on Protein Crystallization DTSTART;VALUE=DATE-TIME:20190128T103000Z DTEND;VALUE=DATE-TIME:20190128T113000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1695@events.saip.org.za DESCRIPTION:Speakers: Wolf-Dieter Schubert (University of Pretoria)\nhttps ://events.saip.org.za/event/145/contributions/1695/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Amissah- Arthur Hall URL:https://events.saip.org.za/event/145/contributions/1695/ END:VEVENT BEGIN:VEVENT SUMMARY:Realising the African Light Source DTSTART;VALUE=DATE-TIME:20190201T114500Z DTEND;VALUE=DATE-TIME:20190201T120000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1696@events.saip.org.za DESCRIPTION:Speakers: Richard Catlow (University College London\; Royal S ociety)\nhttps://events.saip.org.za/event/145/contributions/1696/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1696/ END:VEVENT BEGIN:VEVENT SUMMARY:Structural Targets Annotation Database - STAD DTSTART;VALUE=DATE-TIME:20190130T152000Z DTEND;VALUE=DATE-TIME:20190130T154000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1704@events.saip.org.za DESCRIPTION:Speakers: Abdelkrim RACHEDI (Department of Biology\, Faculty o f Sciences\, Saida University)\nAvailable online at the link: http://www.b ioinformaticstools.org/stad/ (main web-site)\, STAD is a database that ann otates and stores information pertaining to structural targets (mainly pro teins selected for 3d-structure and function elucidation) understudy at la boratories in a number of Algerian\, Moroccan and South African institutes \; refer to Targets Contributing Member Institutes page: http://www.bioinf ormaticstools.org/stad/STsources.php .\n\nThe database is used for trackin g the progress of the targets as they are moved from a step to another unt il their 3d structures are solved and/or work on them has stopped. STAD pr ovides a number of methods for information retrieval\; the ‘Direct’ se arch method can be used to find out detailed information about the sequenc e of the targets\, the stages of their production and structure determinat ion. ‘Patterns/motifs’ search allows for finding targets with certain sequence motifs. Targets with overall sequence similarity to other public sequences are found by using the ‘Sequence Alignment’ search method. I n addition to basic annotation of the targets\, automatic basic structural and functional prediction is carried out and annotated\, for the targets that structure has not been solved yet. Such analyses are also provided in the results page. More tools are provided for further exploration of the targets including a Status\npage\, Statsboard (for overall simple statisti cs\, see main web-site) and a Structural Gallery\; http://www.bioinformati cstools.org/stad/gallery.php?Lab_=All .\nUnless targets are tagged as priv ate based on source lab instructions\, targets’ details from all contrib uting institutes and international public targets together with the\nDocum ent Type Definition (DTD) are made available for download in xml format\; http://www.bioinformaticstools.org/stad/gallery.php?ns=2\n\nhttps://events .saip.org.za/event/145/contributions/1704/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1704/ END:VEVENT BEGIN:VEVENT SUMMARY:MetalJet Source for High-Throughput Screening in the Home Laborato ry DTSTART;VALUE=DATE-TIME:20190128T150000Z DTEND;VALUE=DATE-TIME:20190128T153000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1705@events.saip.org.za DESCRIPTION:Speakers: Emile Espes (N/A)\nHigh-end x-ray diffraction techni ques such as small molecule crystallography\,\nmacromolecular crystallogra phy and non-ambient crystallography rely heavily on the x-ray\nsource brig htness for resolution and exposure time. As boundaries of technology are p ushed\nforward samples are becoming smaller\, weaker diffracting and less stable which put\nadditional requirements on ever brighter sources. With b right enough compact sources\, time\nresolved studies can be achieved even in the home laboratory. Traditional solid or rotating\nanode x-ray tubes are typically limited in brightness by when the e-beam power density melts \nthe anode. The liquid-metal-jet technology has overcome this limitation by using an anode\nthat is already in the molten state thus e-beam power l oading above several megawatts per\nmm are now feasible.\nOver a decade ag o the first prototypes of MetalJet x-ray sources were demonstrated. These\ nimmediately demonstrated unprecedented brightness in the range of one ord er of magnitude\nabove current state-of-the art sources [1-3]. Over the la st years\, the liquid-metal-jet\ntechnology has developed from prototypes into fully operational and stable X-ray tubes\nrunning in more than 75 lab s over the world. X-ray crystallography has been identified as a\nkey appl ication for the x-ray tube technology\, since this application benefits gr eatly from\nsmall spot-sizes\, high-brightness in combination with a need for stable output. To achieve a\nsingle-crystal-diffraction platform addre ssing the needs of the most demanding\ncrystallographers\, multiple users and system manufacturers has since installed the MetalJet x-\nray source i nto their SCD set-ups with successful results [4].\nThis contribution revi ews the evolvement of the MetalJet technology and its applicability\nfor p ushing boundaries of SCD supported by recent user data. We also present po ssibilities to\nachieve cost effective solutions\, attainable for a wider application range. Finally\, we discuss\ndetails of the technology with a focus on its abilities to free up synchrotron time by efficient\nhome labo ratory screening.\n\nhttps://events.saip.org.za/event/145/contributions/17 05/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1705/ END:VEVENT BEGIN:VEVENT SUMMARY:An Overview of the NSLS-II DTSTART;VALUE=DATE-TIME:20190128T110000Z DTEND;VALUE=DATE-TIME:20190128T113000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1706@events.saip.org.za DESCRIPTION:Speakers: Kenenth Evans-Lutterodt (Brookhaven National Labs)\n Synchrotron X-ray sources are having an increasing impact in many aspects of science and engineering. NSLS-II is one of the most recently completed examples of a high brightness synchrotron source. We will give an overview of some of the key features and capabilities of this source\, and similar sources that are currently planned or under construction. Some of the new scientific opportunities that these sources enable will be discussed. Fin ally\, we will discuss the steps that one needs to follow to get access to the capabilities at NSLS-II for your own research.\n\nhttps://events.saip .org.za/event/145/contributions/1706/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryetey Hall URL:https://events.saip.org.za/event/145/contributions/1706/ END:VEVENT BEGIN:VEVENT SUMMARY:Structural study of functional nanomaterials by combining in situ X-ray total scattering and NMR spectroscopy DTSTART;VALUE=DATE-TIME:20190129T143000Z DTEND;VALUE=DATE-TIME:20190129T150000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1707@events.saip.org.za DESCRIPTION:Speakers: Bendeif EL-Eulmi (Université de Lorraine)\nThe conf ined functional molecular nanomaterials have attracted considerable intere st owing to their potential applications in various domains: catalysis\, o ptics\, medicine [1-3]. It is therefore essential to\nstudy the structural organization of such nanomaterials. We will show in this contribution tha t detailed structural information can be obtained by using an appropriate multiscale approach combining various\nexperimental techniques such as X-r ay total scattering coupled to in situ atomic Pair Distribution Function ( PDF) and solid-state NMR spectroscopy. This multiscale approach does provi de more\nextensive and accurate structural information [4-5]. We will also discuss the effect of size reduction on the interesting physical properti es of these functional nanomaterials from a new method we developed\nin ou r laboratory for analysing the PDF data. This method allows extracting and analysing the contributions of different species.\n\nhttps://events.saip. org.za/event/145/contributions/1707/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1707/ END:VEVENT BEGIN:VEVENT SUMMARY:Presentation of the Diffractometers Center of Abidjan DTSTART;VALUE=DATE-TIME:20190130T112000Z DTEND;VALUE=DATE-TIME:20190130T114500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1708@events.saip.org.za DESCRIPTION:Speakers: Abodou Jules Tenon (University Félix Houphouët-Boi gny)\nFirst and foremost\, I would like to express my infinite gratitude t o IUCr\, UNESCO and\nBRUKER for equipping the Abidjan center with a single -crystal diffractometer and a powder\ndiffractometer. These thanks also go to Professor Claude LECOMTE for his great involvement\nin obtaining this material. It should be recalled that the inauguration of this center took place on\nMarch 22 and 23\, 2018 followed by a week-long "Openlab" on the theory and practice of\ndetermination of single-crystal structure and powd er.\nCrystal engineering finds its substance in the determination of struc tures resulting from different\nmodes of synthesis. The knowledge of these structures allows an explanation of their physico-\nchemical properties. The determination of the structures of these compounds is therefore a very \nimportant step for a significant advance in crystal engineering. This is why we are going to\npresent the equipment of the Abidjan diffractometer center which can offer a real contribution to\nthe measurement and the det ermination of the structures resulting from the crystal engineering.\n The presentation of this center will revolve around the equipment and structu res determined\nsince the installation of these diffractometers.\n\nhttps: //events.saip.org.za/event/145/contributions/1708/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1708/ END:VEVENT BEGIN:VEVENT SUMMARY:Structural principles of venom insulins: can these be applied to t he development of new therapies for diabetes? DTSTART;VALUE=DATE-TIME:20190129T114000Z DTEND;VALUE=DATE-TIME:20190129T120000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1709@events.saip.org.za DESCRIPTION:Speakers: Michael Lawrence (Walter and Eliza Hall Inst of Med Res)\nCertain fish-hunting cone snails produce venoms that contain insulin s. These venom insulins facilitate the capture of prey by the rapid induct ion of hypoglycemic shock. We have studied one such insulin\, Conus geogra phus G1 (Con-Ins G1)\, the smallest known insulin in nature. In particular \, Con-Ins G1 lacks the C-terminal segment of the canonical B chain that i n human insulin mediates both receptor engagement and hormone storage. Her e\, we present crystal structures both of the venom insulin itself and of its complex with the primary binding site components of human insulin rece ptor (the latter being a surrogate of fish insulin receptor). Taken togeth er\, these structures suggest principles that may be applicable to the des ign of novel\, ultra-rapid-acting therapeutic insulins.\n\nhttps://events. saip.org.za/event/145/contributions/1709/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Addison Hall URL:https://events.saip.org.za/event/145/contributions/1709/ END:VEVENT BEGIN:VEVENT SUMMARY:The African Light Source Project DTSTART;VALUE=DATE-TIME:20190130T163000Z DTEND;VALUE=DATE-TIME:20190130T165000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1710@events.saip.org.za DESCRIPTION:Speakers: Simon Connell (University of Johannesburg)\nThe glob al science endeavor drives technological development\, which has a large i mpact on socioeconomic development. There are however other benefits: such as the culture of enlightenment\, the eradication of ignorance and prejud ice\, the promotion of large scale boundary-crossing collaborations and a real\, fundamental appreciation of all diversity. In this context\, large- scale research infrastructures play an important role. Amongst these\, one of the most transformative mega-research entities is the modern light sou rce. Research is both fundamental and applied. The former case is a truly universal endeavor\, and in the latter case\, there will be regional prior ities. For all these reasons\, research has to be carried out everywhere\, by all peoples. The passionate belief in this positive role for science i n society has driven the call for the African Light Source. The call was f irst sounded in 2002\, and it has been repeated by many sources on many pl atforms. African scientists are strongly participating in research exploit ing the power of modern light sources\, both from within African instituti ons\, and from other institutions\, as the exercise of the African science diaspora. In addition\, the global science community has also strongly su pported the global proliferation of the benefits of access to large-scale research infrastructures\, and to extending the collaborative participatio n totally. This combination of African and International leadership toward s an African Light Source is embodied in a fully mandated international co mmittee whose vision and project is a Light Source in Africa. This African Light Source would be supported by extensive local and regional research infrastructure and also local and regional human and industrial capacity. This contribution details the progress on the Roadmap towards the African Light Source\, and outlines the future projects\, many of which will be di scussed further in this meeting.\n\nhttps://events.saip.org.za/event/145/c ontributions/1710/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1710/ END:VEVENT BEGIN:VEVENT SUMMARY:Studying ultrafast out-of-equilibrium transformation with time-res olved techniques at synchrotron and X-FEL DTSTART;VALUE=DATE-TIME:20190131T090000Z DTEND;VALUE=DATE-TIME:20190131T100000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1711@events.saip.org.za DESCRIPTION:Speakers: Eric Collet (Université de Rennes 1)\nUltrafast pho toswitching in bistable crystals is associated with a complex transformati on pathway\, multiscale in nature\, where both molecular electronic and st ructural reorganization and macroscopic transformation of the crystal have to be considered [1]. Time-resolved X-ray techniques developing at synchr otron and X-FEL allow for tracking such microscopic transformation on time scales spanning from femtosecond to millisecond and mapping photoinduced s tructural dynamics [2]. We have studied the basic mechanisms allowing ligh t to switch the magnetic molecular state\, from low to high spin through t he activation and damping of molecular breathing [3]. In the active medium \, which the crystal is\, other effects of elastic (propagating) or therma l (diffusive) nature should be considered [1\,4\,5]. In the case of cooper ative solids\, a self-amplified and coherent response to light excitation is observed on short time-scales. This self-amplification process resultin g from the elastic field induced by light and coupled to the molecular vol ume change applies to various types of materials and time-resolved X-ray t echniques play a key role to understand them.\n\n1. R. Bertoni et al\, Na t. Mater.\, 2016\, 15\, 606–610.\n2. M. Chergui and E. Collet\, Chemica l Reviews\, 117 (16)\, 11025–11065 (2017)\n3. H. Lemke et al\, Nature C omm. 2017\, 8\, 15342\n4. R. Bertoni et al\, Cryst. Eng. Comm. 18\, 7269 - 7275 (2016)\n5. C. Mariette et al\, Acta Cryst. B73\, 660-668 (2017)\n\ nCorresponding Author: Eric Collet eric.collet@univ-rennes1.fr\n\nhttps:// events.saip.org.za/event/145/contributions/1711/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1711/ END:VEVENT BEGIN:VEVENT SUMMARY:Science communication: from the CERN example to a wider audience DTSTART;VALUE=DATE-TIME:20190129T150000Z DTEND;VALUE=DATE-TIME:20190129T151500Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1713@events.saip.org.za DESCRIPTION:Speakers: mario campanelli (UCL)\nOne of the missions of parti cle physics laboratories is to foster public interest in the discipline\, explain to the public the results of the research and create a link betwee n the scientists and the public. CERN has a long-standing tradition in out reach and communication with the public\, recently revamped by the use of social media and new initiatives specifically targeting schools. This arti cle will review the various outreach activities from CERN\, and add sugges tions on how to transfer this knowledge to smaller settings.\n\nhttps://ev ents.saip.org.za/event/145/contributions/1713/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1713/ END:VEVENT BEGIN:VEVENT SUMMARY:A Widely Tunable 10-μm QCL Locked to a Metrological Mid-IR Refere nce for Precision Molecular Spectroscopy DTSTART;VALUE=DATE-TIME:20190129T163500Z DTEND;VALUE=DATE-TIME:20190129T164000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1714@events.saip.org.za DESCRIPTION:Speakers: Papa Lat Tabara SOW (Université Alioune DIOP de Bam bey)\nThe quantum cascade lasers (QCL) are popular sources for spectroscop y in the field of mid-infrared because of the wide range of wavelengths th ey can cover (3 μm \n\nhttps://events.saip.org.za/event/145/contributions /1714/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. Ernest Aryeetery Hall URL:https://events.saip.org.za/event/145/contributions/1714/ END:VEVENT BEGIN:VEVENT SUMMARY:Crystallography in Ghana DTSTART;VALUE=DATE-TIME:20190129T080000Z DTEND;VALUE=DATE-TIME:20190129T083000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1715@events.saip.org.za DESCRIPTION:Speakers: Robert Kingsford-Adaboh (University of Ghana)\nCryst allography in Ghana\n\nhttps://events.saip.org.za/event/145/contributions/ 1715/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1715/ END:VEVENT BEGIN:VEVENT SUMMARY:Kinoforms for High Energy Photons DTSTART;VALUE=DATE-TIME:20190129T151500Z DTEND;VALUE=DATE-TIME:20190129T153000Z DTSTAMP;VALUE=DATE-TIME:20260416T021354Z UID:indico-contribution-145-1716@events.saip.org.za DESCRIPTION:Speakers: Kenenth Evans-Lutterodt (Brookhaven National Labs)\n Studying materials with high energy ( > 50 keV ) X-ray photons brings some advantages for materials characterization. For example\, the pair distrib ution function method (PDF) gets better real space resolution with higher energy photons. The ability to focus X-ray beams of high energy photons br ings further experimental benefits for materials characterization\, includ ing greater flux on small samples\, improved signal to background\, and al so enabling spatial scanning of samples. In this talk\, we present our rec ent results using silicon kinoform lenses to focus X-ray photons with ener gies as low as 52keV and as high as 107 keV\, measured on beamlines 1-ID a nd 11-ID-C at the Advanced Photon Source. In a number of experiments\, we have created micron and sub-micron beams\, in some cases as small as 225 n m. Latest improvements in lens fabrication will also be presented. We will also show a numerical comparison between refractive lenses made from Bery llium\, Silicon and Aluminum and kinofom lenses made from Silicon and disc uss the relative merits for these high photon energies.\n\nhttps://events. saip.org.za/event/145/contributions/1716/ LOCATION:Bank of Ghana Conf Facility\, Uni Ghana. URL:https://events.saip.org.za/event/145/contributions/1716/ END:VEVENT END:VCALENDAR